日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Biomarkers in Alzheimer's disease clinical trials: 2025

阿尔茨海默病临床试验中的生物标志物:2025

Osse, Amanda M Leisgang; Zhou, Yadi; Kinney, Jefferson W; Hooyman, Andrew; Sengupta, Ayan; Fonseca, Jorge; Burstein, Aaron H; Owen, Meriel; Nisenbaum, Laura; Fillit, Howard M; Cheng, Feixiong; Cummings, Jeffrey L

Plasma p-tau217 and glucose metabolism correlate in neocortical association areas in Alzheimer's disease

阿尔茨海默病患者新皮质联合区血浆p-tau217与葡萄糖代谢呈正相关

Koenig, Lauren N; Huber, Hanna; Chongtham, Anjalika; Di Molfetta, Guglielmo; Andrews, Randolph D; Lukic, Ana; Shafiian, Neeva; Fillit, Howard M; Blennow, Kaj; Ashton, Nicholas J; Zetterberg, Henrik; Matthews, Dawn C; Pereira, Ana C

Implementing early detection of cognitive impairment in primary care to improve care for older adults

在初级保健中实施认知障碍早期检测,以改善老年人的护理

Fowler, Nicole R; Partrick, Katherine A; Taylor, James; Hornbecker, Michael; Kelleher, Kevin; Boustani, Malaz; Cummings, Jeffrey L; MacLeod, Tim; Mielke, Michelle M; Brosch, Jared R; Lee, Janice; Shobin, Eli; Galvin, James E; Fillit, Howard; Udeh-Momoh, Chinedu; Willis, Deanna R

Risk reduction and precision prevention across the Alzheimer's disease continuum: a systematic review of clinical trials combining multidomain lifestyle interventions and pharmacological or nutraceutical approaches

降低阿尔茨海默病全程风险并进行精准预防:一项结合多领域生活方式干预和药物或营养补充剂疗法的临床试验系统评价

Bereczki, Erika; Mangialasche, Francesca; Barbera, Mariagnese; Padilla, Paola; Hara, Yuko; Fillit, Howard; Solomon, Alina; Kivipelto, Miia

The impact of recent approvals on future alzheimer's disease clinical development: Statistical considerations for combination trials

近期获批药物对未来阿尔茨海默病临床研发的影响:联合用药试验的统计学考量

Dickson, Samuel P; Mallinckrodt, Craig; Burstein, Aaron H; Nisenbaum, Laura; Fillit, Howard M; Zhang, Chenge; Hendrix, Suzanne B

Alzheimer Combination Therapies: Overview and Scenarios

阿尔茨海默病联合疗法:概述和应用场景

Cummings, Jeffrey L; Burstein, Aaron H; Fillit, Howard

Add-on combination therapy with monoclonal antibodies: Implications for drug development

单克隆抗体联合疗法:对药物研发的启示

Cummings, Jeffrey; Burstein, Aaron H; Fillit, Howard

Key considerations for combination therapy in Alzheimer's clinical trials: Perspectives from an expert advisory board convened by the Alzheimer's drug discovery foundation

阿尔茨海默病临床试验中联合疗法的关键考量因素:来自阿尔茨海默病药物研发基金会召集的专家顾问委员会的观点

Cummings, Jeffrey; Gold, Michael; Mintun, Mark; Irizarry, Michael; von Eschenbach, Andrew; Hendrix, Suzanne; Berry, Donald; Sampaio, Cristina; Sink, Kaycee; Landen, Jaren; Kivipelto, Miia; Grundman, Michael; Arnold, Steven E; Green, Allan; Partrick, Katherine; Nisenbaum, Laura; Burstein, Aaron; Fillit, Howard

Harnessing combination therapy: Current treatments, recent advancements, and future directions in Alzheimer's disease

联合疗法的应用:阿尔茨海默病治疗的现状、最新进展和未来方向

Fillit, Howard M; Touchon, Jacques; Vellas, Bruno; Nisenbaum, Laura K; Burstein, Aaron H

Challenges and opportunities for novel combination therapies in Alzheimer's disease: a report from the EU/US CTAD Task Force

阿尔茨海默病新型联合疗法的挑战与机遇:欧盟/美国CTAD工作组报告

Angioni, D; Middleton, L; Bateman, R; Aisen, P; Boxer, A; Sha, S; Zhou, J; Gerlach, I; Raman, R; Fillit, H; Salloway, S; Sperling, R; Vellas, B; Cummings, J