日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multilayered HIV-1 resistance in HSPCs through CCR5 Knockout and B cell secretion of HIV-inhibiting antibodies

通过CCR5敲除和B细胞分泌HIV抑制抗体,造血干细胞中形成多层HIV-1抵抗力

William N Feist # ,Sofia E Luna # ,Kaya Ben-Efraim ,Maria V Filsinger Interrante ,Alvaro Amorin ,Nicole M Johnston ,Theodora U J Bruun ,Ashley Utz ,Hana Y Ghanim ,Benjamin J Lesch ,Theresa M McLaughlin ,Amanda M Dudek ,Matthew H Porteus

Utilizing Machine Learning to Improve Neutralization Potency of an HIV-1 Antibody Targeting the gp41 N-Heptad Repeat

利用机器学习提高靶向 gp41 N-七肽重复序列的 HIV-1 抗体的中和效力

Filsinger Interrante, Maria V; Tang, Shaogeng; Kim, Soohyun; Shanker, Varun R; Hie, Brian L; Bruun, Theodora U J; Wu, Wesley; Pak, John E; Fernandez, Daniel; Kim, Peter S

A broad antibody with enhanced HIV-1 neutralization via bispecific antibody-mediated prepositioning

一种通过双特异性抗体介导的预定位增强HIV-1中和作用的广谱抗体

Kim, Soohyun; Radford, Caelan E; Xu, Duo; Zhong, Jianing; Do, Jonathan; Pham, Dominic M; Travisano, Katie A; Filsinger Interrante, Maria V; Bruun, Theodora U J; Rezek, Valerie; Wilder, Bailey; Palomares, Martina; Seaman, Michael S; Kitchen, Scott G; Bloom, Jesse D; Kim, Peter S

Saponin nanoparticle adjuvants incorporating Toll-like receptor agonists drive distinct immune signatures and potent vaccine responses

含有 Toll 样受体激动剂的皂苷纳米颗粒佐剂可诱导独特的免疫特征和强效的疫苗反应。

Ben S Ou ,Julie Baillet ,Maria V Filsinger Interrante ,Julia Z Adamska ,Xueting Zhou ,Olivia M Saouaf ,Jerry Yan ,John H Klich ,Carolyn K Jons ,Emily L Meany ,Adian S Valdez ,Lauren Carter ,Bali Pulendran ,Neil P King ,Eric A Appel

Enhancing HIV-1 Neutralization by Increasing the Local Concentration of Membrane-Proximal External Region-Directed Broadly Neutralizing Antibodies

通过增加膜近端外部区域定向广谱中和抗体的局部浓度来增强 HIV-1 中和作用

Soohyun Kim, Maria V Filsinger Interrante, Peter S Kim

The high-affinity immunoglobulin receptor FcγRI potentiates HIV-1 neutralization via antibodies against the gp41 N-heptad repeat

高亲和力免疫球蛋白受体FcγRI通过针对gp41 N端七肽重复序列的抗体增强HIV-1的中和作用

Montefiori, David C; Filsinger Interrante, Maria V; Bell, Benjamin N; Rubio, Adonis A; Joyce, Joseph G; Shiver, John W; LaBranche, Celia C; Kim, Peter S

A Derivative of the D5 Monoclonal Antibody That Targets the gp41 N-Heptad Repeat of HIV-1 with Broad Tier-2-Neutralizing Activity

针对 HIV-1 gp41 N-七肽重复序列的 D5 单克隆抗体衍生物,具有广泛的 Tier-2 中和活性

Adonis A Rubio, Maria V Filsinger Interrante, Benjamin N Bell, Clayton L Brown, Theodora U J Bruun, Celia C LaBranche, David C Montefiori, Peter S Kim

Dual display of proteins on the yeast cell surface simplifies quantification of binding interactions and enzymatic bioconjugation reactions

酵母细胞表面蛋白质的双重展示简化了结合相互作用和酶促生物结合反应的量化

Sungwon Lim, Jeff E Glasgow, Maria Filsinger Interrante, Erica M Storm, Jennifer R Cochran

Emerging Strategies for Developing Next-Generation Protein Therapeutics for Cancer Treatment

开发用于癌症治疗的下一代蛋白质疗法的新兴策略

Kintzing, James R; Filsinger Interrante, Maria V; Cochran, Jennifer R

Targeted Drug Delivery with an Integrin-Binding Knottin-Fc-MMAF Conjugate Produced by Cell-Free Protein Synthesis

利用无细胞蛋白质合成产生的整合素结合 Knottin-Fc-MMAF 结合物进行靶向药物输送

Nicolas V Currier, Shelley E Ackerman, James R Kintzing, Rishard Chen, Maria Filsinger Interrante, Alexander Steiner, Aaron K Sato, Jennifer R Cochran