日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

First-In-Human Phase I Study Of A Dual mTOR Kinase And DNA-PK Inhibitor (CC-115) In Advanced Malignancy

针对晚期恶性肿瘤的双重 mTOR 激酶和 DNA-PK 抑制剂 (CC-115) 的首次人体 I 期研究

Munster, Pamela; Mita, Monica; Mahipal, Amit; Nemunaitis, John; Massard, Christophe; Mikkelsen, Tom; Cruz, Cristina; Paz-Ares, Luis; Hidalgo, Manuel; Rathkopf, Dana; Blumenschein, George Jr; Smith, David C; Eichhorst, Barbara; Cloughesy, Tim; Filvaroff, Ellen H; Li, Shaoyi; Raymon, Heather; de Haan, Hans; Hege, Kristen; Bendell, Johanna C

A technology platform to assess multiple cancer agents simultaneously within a patient's tumor

一种用于同时评估患者肿瘤内多种抗癌药物的技术平台

Klinghoffer, Richard A; Bahrami, S Bahram; Hatton, Beryl A; Frazier, Jason P; Moreno-Gonzalez, Alicia; Strand, Andrew D; Kerwin, William S; Casalini, Joseph R; Thirstrup, Derek J; You, Sheng; Morris, Shelli M; Watts, Korashon L; Veiseh, Mandana; Grenley, Marc O; Tretyak, Ilona; Dey, Joyoti; Carleton, Michael; Beirne, Emily; Pedro, Kyle D; Ditzler, Sally H; Girard, Emily J; Deckwerth, Thomas L; Bertout, Jessica A; Meleo, Karri A; Filvaroff, Ellen H; Chopra, Rajesh; Press, Oliver W; Olson, James M

TGF-beta regulates the mechanical properties and composition of bone matrix

TGF-β调节骨基质的力学性能和组成

Balooch, Guive; Balooch, Mehdi; Nalla, Ravi K; Schilling, Stephen; Filvaroff, Ellen H; Marshall, Grayson W; Marshall, Sally J; Ritchie, Robert O; Derynck, Rik; Alliston, Tamara

Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus.

丝氨酸/苏氨酸激酶融合蛋白的缺失会导致出生后生长缺陷,并因进行性脑积水而导致死亡

Merchant Mark, Evangelista Marie, Luoh Shiuh-Ming, Frantz Gretchen D, Chalasani Sreedevi, Carano Richard A D, van Hoy Marjie, Ramirez Julio, Ogasawara Annie K, McFarland Leanne M, Filvaroff Ellen H, French Dorothy M, de Sauvage Frederic J

Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover

血管内皮生长因子通过促进血管生成和骨转换来刺激骨修复。

Street, John; Bao, Min; deGuzman, Leo; Bunting, Stuart; Peale, Franklin V Jr; Ferrara, Napoleone; Steinmetz, Hope; Hoeffel, John; Cleland, Jeffrey L; Daugherty, Ann; van Bruggen, Nicholas; Redmond, H Paul; Carano, Richard A D; Filvaroff, Ellen H