日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Somatic mutation in human cerebellum illustrates neuron type-specific patterns of age-related mutation

人类小脑的体细胞突变揭示了与年龄相关的神经元类型特异性突变模式

Essuman, Kow; Yang, Yingxi; Goodman, Eitan; Cambridge, Christie N; Cai, Chunhui; An, Zheming; Mao, Shulin; Manam, Monica Devi; Finander, Benjamin; Khoshkhoo, Sattar; Sun, Liang; Huang, August Yue; Walsh, Christopher A

Activating Ras-MAPK pathway variants drive hippocampal clonal competition in human epilepsy

激活Ras-MAPK通路变体驱动人类癫痫海马克隆竞争

Khoshkhoo, Sattar; Bae, Mingyun; Wang, Yilan; Tillett, Ashton; Ramirez, Rosita B; Finander, Benjamin; Egan, Emily D; Marx, Linus; Patel, Dipan; Zhou, Zinan; Chahine, Yasmine; Chhouk, Brian; Zoullas, Sofia M; Lai, Abbe; Coras, Roland; Bielle, Franck; Navarro, Vincent; Mathon, Bertrand; Valiante, Taufik A; Moradi Chameh, Homeira; Gao, Andrew F; Krings, Timo; Gooley, Samuel; Hildebrand, Michael S; Bulluss, Kristian; Clark, Jonathan; Morokoff, Andrew P; King, James A; Todaro, Marian; Kwan, Patrick; O'Brien, Terence J; Berkovic, Samuel F; Scheffer, Ingrid E; Perucca, Piero; Lapinskas, Emily; Rolston, John D; Cosgrove, G Rees; Sarkis, Rani A; D'Gama, Alissa M; Alexadrescu, Sanda; Yang, Edward; Poduri, Annapurna; Richardson, R Mark; Erson-Omay, E Zeynep; DeLanerolle, Nihal; Spencer, Dennis D; Brown, Katherine S-M; Miller, Michael B; Roberts, Amy E; Santos, Luana N; Kontaridis, Maria I; Bien, Christian G; Blacklow, Stephen C; Kahle, Kristopher T; Blümcke, Ingmar; Huang, August Yue; Lee, Eunjung Alice; Walsh, Christopher A

Cell-type-informed genotyping of mosaic focal epilepsies reveals cell-autonomous and non-cell-autonomous disease-associated transcriptional programs

基于细胞类型信息的嵌合型局灶性癫痫基因分型揭示了细胞自主性和非细胞自主性的疾病相关转录程序

Bizzotto, Sara; Talukdar, Maya; Stronge, Edward A; Ramirez, Rosita B; Yang, Yingxi; Huang, August Yue; Hu, Qiwen; Hou, Yingping; Hylton, Norma K; Finander, Benjamin; Tillett, Ashton; Zhou, Zinan; Chhouk, Brian H; D'Gama, Alissa M; Yang, Edward; Green, Timothy E; Reutens, David C; Mullen, Saul A; Scheffer, Ingrid E; Hildebrand, Michael S; Buono, Russell J; Blümcke, Ingmar; Poduri, Annapurna H; Khoshkhoo, Sattar; Walsh, Christopher A

Neuronal activity triggers widespread changes in RNA stability

神经元活动引发RNA稳定性的广泛变化

Duffy, Erin E; Patop, Inés L; Kalaora, Shelly; Assad, Elena G; Koren, Shon A; Traunmüller, Lisa; Krüttner, Sebastian; Pajarillo, Naeem S; Finander, Benjamin; Barsdale, Zachary; Macias, Mia M; Feng, Min Yi; Paulo, Joao A; Griffith, Eric C; Kalish, Brian T; Gygi, Steven P; Churchman, L Stirling; Greenberg, Michael E

Ultrastructure of Synaptic Connectivity within Subregions of the Suprachiasmatic Nucleus Revealed by a Genetically Encoded Tag and Serial Blockface Electron Microscopy

利用基因编码标签和连续切片电子显微镜揭示视交叉上核亚区突触连接的超微结构

Calligaro, Hugo; Shoghi, Azarin; Chen, Xinyue; Kim, Keun-Young; Yu, Hsin Liu; Khov, Brian; Finander, Benjamin; Le, Hiep; Ellisman, Mark H; Panda, Satchidananda

TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system

TMEM161B 调节发育中中枢神经系统的大脑皮层回旋、Sonic Hedgehog 信号和纤毛结构

Shyam K Akula, Jack H Marciano, Youngshin Lim, David Exposito-Alonso, Norma K Hylton, Grace H Hwang, Jennifer E Neil, Nicole Dominado, Rosie K Bunton-Stasyshyn, Janet H T Song, Maya Talukdar, Aloisia Schmid, Lydia Teboul, Alisa Mo, Taehwan Shin, Benjamin Finander, Samantha G Beck, Rebecca C Yeh, Aoi

Developmental dynamics of RNA translation in the human brain

人类大脑中RNA翻译的发育动态

Erin E Duffy ,Benjamin Finander ,GiHun Choi ,Ava C Carter ,Iva Pritisanac ,Aqsa Alam ,Victor Luria ,Amir Karger ,William Phu ,Maxwell A Sherman ,Elena G Assad ,Naomi Pajarillo ,Alexandra Khitun ,Elizabeth E Crouch ,Sanika Ganesh ,Jin Chen ,Bonnie Berger ,Nenad Sestan ,Anne O'Donnell-Luria ,Eric J Huang ,Eric C Griffith ,Julie D Forman-Kay ,Alan M Moses ,Brian T Kalish ,Michael E Greenberg

Repetitive Mild Closed Head Injury in Adolescent Mice Is Associated with Impaired Proteostasis, Neuroinflammation, and Tauopathy

青春期小鼠反复轻度闭合性头部损伤与蛋白质稳态受损、神经炎症和 Tau 蛋白病有关

Limin Wu, Brian T Kalish, Benjamin Finander, Tian Cao, Gina Jin, Taha Yahya, Emily S Levy, Bharti Kukreja, Eliza Sophie LaRovere, Joon Yong Chung, Eng H Lo, Alexander Brown-Whalen, Joseph El Khoury, David L Kaplan, Michael J Whalen1

Single-cell immunophenotyping of the fetal immune response to maternal SARS-CoV-2 infection in late gestation

妊娠晚期胎儿对母体 SARS-CoV-2 感染的免疫反应的单细胞免疫表型分析

Juan D Matute, Benjamin Finander, David Pepin, Xingbin Ai, Neal P Smith, Jonathan Z Li, Andrea G Edlow, Alexandra-Chloe Villani, Paul H Lerou, Brian T Kalish0

Maternal immune activation in mice disrupts proteostasis in the fetal brain

小鼠母体免疫激活破坏胎儿大脑的蛋白质稳态

Brian T Kalish #, Eunha Kim #, Benjamin Finander, Erin E Duffy, Hyunju Kim, Casey K Gilman, Yeong Shin Yim, Lilin Tong, Randal J Kaufman, Eric C Griffith, Gloria B Choi, Michael E Greenberg, Jun R Huh