Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBFβ interaction
通过定量高通量筛选 RUNX1-CBFβ 相互作用鉴定苯二氮卓类药物 Ro5-3335 为 CBF 白血病抑制剂
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.1200037109
Lea Cunningham, Steven Finckbeiner, R Katherine Hyde, Noel Southall, Juan Marugan, Venkat R K Yedavalli, Seameen Jean Dehdashti, William C Reinhold, Lemlem Alemu, Ling Zhao, Jing-Ruey Joanna Yeh, Raman Sood, Yves Pommier, Christopher P Austin, Kuan-Teh Jeang, Wei Zheng, Paul Liu
