日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pseudohypoxia-Stabilized HIF2α Transcriptionally Inhibits MNRR1, a Druggable Target in MELAS.

假性缺氧稳定 HIF2α 转录抑制 MNRR1,MNRR1 是 MELAS 中的可药物靶点

Purandare Neeraja, Pasupathi Vignesh, Xi Yue, Rajan Vikram, Vegh Caleb, Firestine Steven, Kozicz Tamas, Fribley Andrew M, Grossman Lawrence I, Aras Siddhesh

Bile Acid Analogs with Anti-Germination Activities for Prophylaxis of Clostridioides difficile Infection Alter Bile Acid Homeostasis in the Enterohepatic Cycle

具有抗细菌萌发活性的胆汁酸类似物可用于预防艰难梭菌感染,但会改变肠肝循环中的胆汁酸稳态。

Vakeesan, Nivisa; Heredia, Efren; Hassan, Chandler; Jiang, Yang; Sharma, Shiv; Su, Lianyong; Zhou, Huiping; Firestine, Steven; Abel-Santos, Ernesto; Liu, Wanqing

A Fragment-Based Screen for Inhibitors of Escherichia coli N5-CAIR Mutase

基于片段的大肠杆菌N5-CAIR变位酶抑制剂筛选

Sharma, Marcella F; Firestine, Steven

A Fluorescence-Based Assay for N(5) -Carboxyaminoimidazole Ribonucleotide Mutase

基于荧光法的N(5)-羧氨基咪唑核糖核苷酸变位酶检测

Sharma, Marcella F; Sharma, Shiv K; Streeter, Cale C; Firestine, Steven M

An Aniline-Substituted Bile Salt Analog Protects both Mice and Hamsters from Multiple Clostridioides difficile Strains

苯胺取代的胆汁酸类似物可保护小鼠和仓鼠免受多种艰难梭菌菌株的感染

Phan, Jacqueline R; Do, Dung M; Truong, Minh Chau; Ngo, Connie; Phan, Julian H; Sharma, Shiv K; Schilke, Angel; Mefferd, Chrisabelle C; Villarama, Jacob V; Lai, Dengxun; Consul, Amber; Hedlund, Brian P; Firestine, Steven M; Abel-Santos, Ernesto

The Design, Synthesis, and Characterizations of Spore Germination Inhibitors Effective against an Epidemic Strain of Clostridium difficile

针对流行性艰难梭菌菌株的有效孢子萌发抑制剂的设计、合成和表征

Sharma, Shiv K; Yip, Christopher; Esposito, Emilio Xavier; Sharma, Prateek V; Simon, Matthew P; Abel-Santos, Ernesto; Firestine, Steven M

Site-directed mutagenesis of catalytic residues in N(5)-carboxyaminoimidazole ribonucleotide synthetase

N(5)-羧基氨基咪唑核糖核苷酸合成酶催化残基的定点诱变

Dewal, Mahender B; Firestine, Steven M

The ATP-grasp enzymes

ATP结合酶

Fawaz, Maria V; Topper, Melissa E; Firestine, Steven M

Development of a neuroscience-oriented "methods" course for graduate students of pharmacology and toxicology

为药理学和毒理学研究生开发一门以神经科学为导向的“方法”课程

Surratt, Christopher K; Witt-Enderby, Paula A; Johnson, David A; Anderson, Carl A; Bricker, J Douglas; Davis, Vicki L; Firestine, Steven M; Meng, Wilson S