Inhibition of HDAC7 reprograms the histone H3.3 landscape to induce heterochromatin spreading and DNA replication defects in cancer cells
抑制 HDAC7 可重编程组蛋白 H3.3 结构,从而诱导癌细胞中异染色质扩散和 DNA 复制缺陷。
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110732
Hassan, Ola; Pizzagalli, Mattia; Leary, Owen P; Zepecki, John P; Corseri, Adrianne; Wu, Laura Jinxuan; Sasipalli, Shiven; Lee, Daniel; Hayward, Lindsey; Tran, Lily; Fajardo, Eduardo; Fiser, Andras; Karambizi, David; Tapinos, Nikos