日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Optimization of a sarbecovirus llama nanobody-antigen binding interface via a combined computational and phage display protein engineering approach

通过结合计算和噬菌体展示蛋白工程方法优化沙贝病毒羊驼纳米抗体-抗原结合界面

Ramos, Kevin E; Nandigrami, Prithviraj; Najafian, Ahmad; Lai, Jonathan R; Fiser, Andras

Overcoming research bias: The untapped potential of biomedically important but understudied proteins

克服研究偏见:生物医学上重要但研究不足的蛋白质的未开发潜力

Grudman, Steven; Madrid-Aliste, Carlos; Fiser, Andras

Inhibition of HDAC7 reprograms the histone H3.3 landscape to induce heterochromatin spreading and DNA replication defects in cancer cells

抑制 HDAC7 可重编程组蛋白 H3.3 结构,从而诱导癌细胞中异染色质扩散和 DNA 复制缺陷。

Hassan, Ola; Pizzagalli, Mattia; Leary, Owen P; Zepecki, John P; Corseri, Adrianne; Wu, Laura Jinxuan; Sasipalli, Shiven; Lee, Daniel; Hayward, Lindsey; Tran, Lily; Fajardo, Eduardo; Fiser, Andras; Karambizi, David; Tapinos, Nikos

Mechanistic insights into mutation in the proton-coupled folate transporter (SLC46A1) causing hereditary folate malabsorption

对导致遗传性叶酸吸收不良的质子偶联叶酸转运蛋白(SLC46A1)突变的机制性见解

Nandigrami, Prithviraj; Goldman, I David; Fiser, Andras

GliaTrap is a biodegradable, non-swelling and non-inflammatory hydrogel with tuned release of CXCL12 to attract migrating glioblastoma cells.

GliaTrap 是一种可生物降解、不膨胀、不引起炎症的水凝胶,可调控释放 CXCL12 以吸引迁移的胶质母细胞瘤细胞

Suita Yusuke, Miriyala Saradha, Merih-Toruner Deniz, Pizzagalli Mattia, Leary Owen P, Yue Weizhou, Xie Lingxiao, Akobundu Blessing, Pertsch Nathan, Fiser Andras, Fajardo Eduardo, Shen Jie, Tapinos Nikos

Assessing the functional impact of protein binding site definition

评估蛋白质结合位点定义的功能影响

Nandigrami, Prithviraj; Fiser, Andras

Role of the Egr2 Promoter Antisense RNA in Modulating the Schwann Cell Chromatin Landscape

Egr2启动子反义RNA在调控雪旺细胞染色质结构中的作用

Martinez Moreno, Margot; Karambizi, David; Hwang, Hyeyeon; Fregoso, Kristen; Michles, Madison J; Fajardo, Eduardo; Fiser, Andras; Tapinos, Nikos

MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues

幽门螺杆菌MAT活性获得性突变与MTAN过渡态类似物的耐药性相关

Feng, Mu; Namanja-Magliano, Hilda; Rajagopalan, Saranathan; Mishra, Tanmay; Ducati, Rodrigo G; Hirsch, Brett M; Kelly, Libusha; Szymczak, Wendy; Fajardo, Jorge Eduardo; Sidoli, Simone; Fiser, Andras; Jacobs, William R; Schramm, Vern L

Cell fate decisions, transcription factors and signaling during early retinal development

视网膜早期发育过程中的细胞命运决定、转录因子和信号传导

Diacou, Raven; Nandigrami, Prithviraj; Fiser, Andras; Liu, Wei; Ashery-Padan, Ruth; Cvekl, Ales

INTERCAAT: identifying interface residues between macromolecules

INTERCAAT:识别大分子间的界面残基

Grudman, Steven; Fajardo, J Eduardo; Fiser, Andras