日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In vitro and computational approaches to predict developmental toxicity: Integrating PBPK models with cell-based assays

利用体外和计算方法预测发育毒性:将PBPK模型与基于细胞的检测相结合

Moreau, Marjory; Antonijevic, Todor; Hall, John Carter; Fisher, Jeffrey

The Feasibility and Acceptability of a Clinical Pharmacist-delivered Intervention to Reduce Bothersome Health Symptoms from Polypharmacy and Alcohol Use and Communicate Risk among People with HIV: Pilot Study Protocol

临床药师干预措施在减少艾滋病毒感染者多重用药和酒精滥用引起的不良健康症状及风险沟通方面的可行性和可接受性:试点研究方案

Womack, Julie A; Leblanc, Micaela M; Sager, Annette S; Zaets, Lauren N; Maisto, Stephen A; Garcia, Adelyn; Aoun-Barakat, Lydia; Brown, Shan-Estelle; Edelman, E Jennifer; Fiellin, David A; Fisher, Jeffrey; Fraenkel, Liana; Kidwai-Khan, Farah; Marconi, Vincent C; Martino, Steve; Pulk, Rebecca; Satre, Derek D; Virata, Michael; Justice, Amy C; Hsieh, Evelyn

Immune checkpoint landscape of human atherosclerosis and influence of cardiometabolic factors

人类动脉粥样硬化的免疫检查点图谱及其受心血管代谢因素的影响

José Gabriel Barcia Durán # ,Dayasagar Das # ,Michael Gildea ,Letizia Amadori ,Morgane Gourvest ,Ravneet Kaur ,Natalia Eberhardt ,Panagiotis Smyrnis ,Burak Cilhoroz ,Swathy Sajja ,Karishma Rahman ,Dawn M Fernandez ,Peter Faries ,Navneet Narula ,Rami Vanguri ,Ira J Goldberg ,Edward A Fisher ,Jeffrey S Berger ,Kathryn J Moore ,Chiara Giannarelli

Use of quantitative in vitro to in vivo extrapolation (QIVIVE) for the assessment of non-combustible next-generation product aerosols

利用定量体外到体内外推法(QIVIVE)评估不可燃的下一代产品气溶胶

Moreau, Marjory; Simms, Liam; Andersen, Melvin E; Trelles Sticken, Edgar; Wieczorek, Roman; Pour, Sarah Jean; Chapman, Fiona; Roewer, Karin; Otte, Sandra; Fisher, Jeffrey; Stevenson, Matthew

In vitro to in vivo extrapolation from 3D hiPSC-derived cardiac microtissues and physiologically based pharmacokinetic modeling to inform next-generation arrhythmia risk assessment.

从体外到体内,利用 3D hiPSC 衍生的心脏微组织和基于生理的药代动力学模型,为下一代心律失常风险评估提供信息

Daley Mark C, Moreau Marjory, Bronk Peter, Fisher Jeffrey, Kofron Celinda M, Mende Ulrike, McMullen Patrick, Choi Bum-Rak, Coulombe Kareen

Hyperchylomicronemia causes endothelial cell inflammation and increases atherosclerosis

乳糜微粒血症导致内皮细胞炎症并增加动脉粥样硬化

Maria Concepcion Izquierdo, Ainara G Cabodevilla, Debapriya Basu, Dimitris Nasias, Jenny E Kanter, Winnie Ho, Jana Gjini, Edward A Fisher, Jeffrey Kim, Warren Lee, Karin E Bornfeldt, Ira J Goldberg

Animal-free assessment of developmental toxicity: Combining PBPK modeling with the ReproTracker assay

无动物实验评估发育毒性:将PBPK模型与ReproTracker检测相结合

Moreau, Marjory; Jamalpoor, Amer; Hall, John Carter; Fisher, Jeffrey; Hartvelt, Sabine; Hendriks, Giel; Nong, Andy

The structure of caseinolytic protease subunit ClpP2 reveals a functional model of the caseinolytic protease system from Chlamydia trachomatis

酪蛋白水解蛋白酶亚基 ClpP2 的结构揭示了沙眼衣原体酪蛋白水解蛋白酶系统的功能模型

Jahaun Azadmanesh, Mohamed A Seleem, Lucas Struble, Nicholas A Wood, Derek J Fisher, Jeffrey J Lovelace, Antonio Artigues, Aron W Fenton, Gloria E O Borgstahl, Scot P Ouellette, Martin Conda-Sheridan

Towards translating in vitro measures of thyroid hormone system disruption to in vivo responses in the pregnant rat via a biologically based dose response (BBDR) model

通过基于生物学的剂量反应(BBDR)模型,将体外甲状腺激素系统紊乱的测量结果转化为妊娠大鼠体内的反应。

Fisher, Jeffrey; Housand, Conrad; Mattie, David; Nong, Andy; Moreau, Marjory; Gilbert, Mary

Considerations for Applying Route-to-Route Extrapolation to Assess the Safety of Oral Exposure to Substances

应用途径间推断法评估口服接触物质安全性的注意事项

Kabadi, Shruti V; Fisher, Jeffrey; Hung, Benjamin; Aungst, Jason