日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Data-Independent Acquisition (DIA) Strategy for Measuring Protein Stability Using Stability of Proteins from Rates of Oxidation (SPROX)

利用蛋白质氧化速率稳定性 (SPROX) 测量蛋白质稳定性的数据非依赖性采集 (DIA) 策略

Labbe, Natalie M; Virani, Meghan K; Fitzgerald, Michael C

Extrinsic and intrinsic factors affect copper-induced protein precipitation across eukaryotic and prokaryotic proteomes

外在因素和内在因素都会影响铜诱导的真核生物和原核生物蛋白质组的蛋白质沉淀。

Sturrock, Grace R; Robison, Amy T R; Dharani, Azim; Monson, Eric E; Franz, Katherine J; Fitzgerald, Michael C

Covalent inhibition of Plasmodium falciparum Ubc13 impairs global protein synthesis.

疟原虫 Ubc13 的共价抑制会损害整体蛋白质合成

Truong Anna, Hu Ruitian, Quan Baiyi, Bailey Morgan A, Schroeder Erin A, Sylvester Kayla, Neveu Gaëlle, Kafsack Björn F C, Fitzgerald Michael C, Derbyshire Emily R

Leveraging Vulnerabilities in Copper Trafficking for Synergistic Antifungal Activity

利用铜走私漏洞实现协同抗真菌活性

Denning-Jannace, Catherine A; James, Katherine J; Monteagudo, Carlos R; Sturrock, Grace R; Robison, Amy T R; Vaccaro, Francesca A; Kuhn, Sophia A; Fitzgerald, Michael C; Franz, Katherine J

Copper Activates a Redox Switch to Reversibly Inhibit Glyceraldehyde-3-Phosphate Dehydrogenase

铜激活氧化还原开关,可逆地抑制甘油醛-3-磷酸脱氢酶

Outlaw, Taylor C; Robison, Amy T R; Schulte, Natalie B; Vaccaro, Francesca A; Williams, Isabella G; Repala, Swara; Diaz, Diego; Sturrock, Grace R; Fitzgerald, Michael C; Franz, Katherine J

Discovery of Host-Directed Small Molecules with Broad Anti-Leishmanial Efficacy

发现具有广谱抗利什曼原虫功效的宿主导向型小分子

Gurysh, Elizabeth G; Zahid, M Shamim Hasan; Johnson, Monica M; Landavazo, Antonio; Namjoshi, Ojas A; Wilson, Joseph W; Varma, Devika M; Woodring, Ryan N; Hendricksen, Aaron T; Vath, Joseph F; Quan, Baiyi; Pino, Erica N; Fitzgerald, Michael C; Bachelder, Eric M; Blough, Bruce E; Ainslie, Kristy M

Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome.

选择性靶向恶性疟原虫 Hsp90 可破坏 26S 蛋白酶体

Mansfield Christopher R, Quan Baiyi, Chirgwin Michael E, Eduful Benjamin, Hughes Philip F, Neveu Gaëlle, Sylvester Kayla, Ryan Daniel H, Kafsack Björn F C, Haystead Timothy A J, Leahy James W, Fitzgerald Michael C, Derbyshire Emily R

Top-Down Stability of Proteins from Rates of Oxidation (TD-SPROX) Approach for Measuring Proteoform-Specific Folding Stability

基于氧化速率的自上而下蛋白质稳定性(TD-SPROX)方法用于测量蛋白质异构体特异性折叠稳定性

Zou, You; Huang, Che-Fan; Sturrock, Grace R; Kelleher, Neil L; Fitzgerald, Michael C

Stability-Based Proteomics for Investigation of Structured RNA-Protein Interactions

基于稳定性的蛋白质组学在结构化RNA-蛋白质相互作用研究中的应用

Bailey, Morgan A; Martyr, Justin G; Hargrove, Amanda E; Fitzgerald, Michael C

Analysis of Brain Protein Stability Changes in a Mouse Model of Alzheimer's Disease.

阿尔茨海默病小鼠模型脑蛋白稳定性变化分析

Tang Yun, Park Hye-Jin, Li Shengyu, Fitzgerald Michael C