日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A cysteine-less and ultra-fast split intein rationally engineered from being aggregation-prone to highly efficient in protein trans-splicing

一种不含半胱氨酸的超快速分裂内含肽,经合理设计使其从易聚集状态转变为高效的蛋白质反式剪接形式。

Humberg, Christoph; Yilmaz, Zahide; Fitzian, Katharina; Dörner, Wolfgang; Kümmel, Daniel; Mootz, Henning D

TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation

TSC1 与溶酶体 PIP 结合是 TSC 复合物易位和 mTORC1 调节所必需的

Katharina Fitzian, Anne Brückner, Laura Brohée, Reinhard Zech, Claudia Antoni, Stephan Kiontke, Raphael Gasper, Anna Livia Linard Matos, Stephanie Beel, Sabine Wilhelm, Volker Gerke, Christian Ungermann, Mark Nellist, Stefan Raunser, Constantinos Demetriades, Andrea Oeckinghaus, Daniel Kümmel