Fitzpatrick Mackenzie K相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

An Adcy3 coding mutation causes partial loss of enzymatic function, contributing to obesity in a rat model by reducing lipolysis

Adcy3 编码突变导致酶功能部分丧失，通过降低脂肪分解作用，在大鼠模型中引起肥胖。

doi:10.21203/rs.3.rs-8309561/v1

Fitzpatrick, Mackenzie K; Seshie, Osborne; Scott, Christina; Vora, Anusha; Seramur, Mary E; Beeson, Angela; Adrian, Leighelle; Grzybowski, Michael; Klotz, Jason; Geurts, Aron M; Key, Chia-Chi Chuang; Woods, Leah C Solberg

发表日期：2026

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A Mutation in the Transmembrane Domain of Adenylate Cyclase 3 Impairs Enzymatic Function to Cause Sex-Specific Depression- and Anxiety-Like Behaviors and Food Seeking in a Rat Model.

腺苷酸环化酶 3 跨膜结构域的突变会损害酶功能，导致大鼠模型出现性别特异性的抑郁和焦虑样行为以及觅食行为

期刊:Genes Brain and Behavior

影响因子:2.3

doi:10.1111/gbb.70028

Fitzpatrick Mackenzie K, Dyson Christina, Beeson Angela, Adrian Leighelle, Marrs Glen, Grzybowski Michael, Klotz Jason, Geurts Aron M, Chen Rong, Weiner Jeffrey L, Solberg Woods Leah C

免疫/内分泌

发表日期：2025

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A mutation in the transmembrane domain of Adenylate cyclase 3 impairs enzymatic function to cause sex-specific depression- and anxiety-like behaviors and food seeking in a rat model

腺苷酸环化酶3跨膜结构域的突变会损害酶功能，导致大鼠模型出现性别特异性的抑郁和焦虑样行为以及觅食行为。

doi:10.1101/2025.03.28.645767

Fitzpatrick, Mackenzie K; Dyson, Christina; Beeson, Angela; Adrian, Leighelle; Marrs, Glen; Grzybowski, Michael; Klotz, Jason; Geurts, Aron M; Chen, Rong; Weiner, Jeffrey L; Solberg Woods, Leah C

发表日期：2025

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Protein-coding mutation in Adcy3 increases adiposity and alters emotional behaviors sex-dependently in rats

Adcy3蛋白编码突变会增加大鼠的脂肪堆积并改变其情绪行为，且这种改变具有性别依赖性。

doi:10.1002/oby.24178

Fitzpatrick, Mackenzie K; Szalanczy, Alexandria; Beeson, Angela; Vora, Anusha; Scott, Christina; Grzybowski, Michael; Klotz, Jason; Der, Nataley; Chen, Rong; Geurts, Aron M; Solberg Woods, Leah C

发表日期：2025

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