The F508del-CFTR trafficking correctors elexacaftor and tezacaftor are CFTR-independent Ca2+-mobilizing agonists normalizing abnormal Ca2+ levels in human airway epithelial cells
F508del-CFTR 运输校正剂 elexacaftor 和 tezacaftor 是 CFTR 独立的 Ca2+ 动员激动剂,可使人类呼吸道上皮细胞中的异常 Ca2+ 水平正常化
期刊:Respiratory Research
影响因子:6.6
doi:10.1186/s12931-024-03059-8
Manuella Lévêque, Sandra Mirval, Christine Barrault, Isabelle Fixe, Christelle Coraux, Edouard Sage, Frédéric Becq, Clarisse Vandebrouck