日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Proinflammatory Secretome of Senescent Cells Can Be Controlled by a HIF2A-Dependent Upregulation and a FURIN-Dependent Cleavage of the ANGPTL4 Secreted Factor.

衰老细胞的促炎分泌组可通过 HIF2A 依赖性上调和 FURIN 依赖性切割 ANGPTL4 分泌因子来控制。

Makulyte Gabriela, Safwan-Zaiter Hasan, Goehrig Delphine, Huna Anda, Mangelinck Adèle, Mikawa Takumi, Palazzo Alberta, Moudombi Lyvia, Medard Jean-Jacques, Chanal Marie, Lecot Pacôme, Michallet Marie-Cécile, Gavard Julie, Adnot Serge, Dubus Pierre, Kondoh Hiroshi, Mann Carl, Tan Nguan Soon, Bertolino Philippe, Flaman Jean-Michel, Bernard David

Virus-Induced Cellular Senescence Causes Pulmonary Sequelae Post-Influenza Infection.

病毒诱导的细胞衰老导致流感感染后肺部后遗症

Lipskaia Larissa, Delval Lou, Sencio Valentin, Born Emmanuelle, Heumel Séverine, Houssaini Amal, Valentin Clara, Raviola Stefano, Deruyter Lucie, Angulo Fabiola Silva, Gros Vincent, Marcos Elisabeth, Abid Shariq, Goekyildirim Mira, Contreras Vanessa, Flaman Jean Michel, Le Grand Roger, Le Goffic Ronan, Bernard David, Adnot Serge, Trottein François

Primary cutaneous NUT adnexal carcinoma: morphologic, genetic and methylation analysis of seven new cases with comparison to extracutaneous NUT carcinoma and NUTM1-rearranged porocarcinoma

原发性皮肤NUT附属器癌:7例新病例的形态学、遗传学和甲基化分析,并与皮肤外NUT癌和NUTM1重排汗孔癌进行比较

Legrand, Mélanie; Louveau, Baptiste; Osio, Amélie; Tallet, Anne; Calonje, Eduardo; Scoazec, Jean-Yves; de la Fouchardiere, Arnaud; Tirode, Franck; Von Deimling, Andreas; Busam, Klaus; Shah, Ahmed; Flaman, Ashley; Jouenne, Fanélie; Mourah, Samia; Pissaloux, Daniel; Lantuejoul, Sylvie; French, Christopher A; Goto, Keisuke; Cribier, Bernard; Dehner, Carina A; Alomari, Ahmed K; Fletcher, Christopher Dm; Hanna, John; Macagno, Nicolas; Battistella, Maxime; Kervarrec, Thibault

A non-canonical role of ELN protects from cellular senescence by limiting iron-dependent regulation of gene expression

ELN 的非典型作用是通过限制铁依赖性基因表达调控来防止细胞衰老

Joanna Czarnecka-Herok, Kexin Zhu, Jean-Michel Flaman, Delphine Goehrig, Mathieu Vernier, Gabriela Makulyte, Aline Lamboux, Helena Dragic, Muriel Rhinn, Jean-Jacques Médard, Gilles Faury, Philippe Bertolino, Vincent Balter, Romain Debret, Serge Adnot, Nadine Martin, David Bernard

Regulation of cell function and identity by cellular senescence

细胞衰老对细胞功能和身份的调控

Huna, Anda; Massemin, Amélie; Makulyte, Gabriela; Flaman, Jean-Michel; Martin, Nadine; Bernard, David

Inhibition of Vascular Smooth Muscle Cell Proliferation by ENPP1: The Role of CD73 and the Adenosine Signaling Axis

ENPP1 抑制血管平滑肌细胞增殖:CD73 和腺苷信号轴的作用

Boris Tchernychev, Yvonne Nitschke, Di Chu, Caitlin Sullivan, Lisa Flaman, Kevin O'Brien, Jennifer Howe, Zhiliang Cheng, David Thompson, Daniel Ortiz, Frank Rutsch, Yves Sabbagh

Immune profiling of dedifferentiated liposarcoma and identification of novel antigens for targeted immunotherapy

去分化脂肪肉瘤的免疫分析和靶向免疫治疗新抗原的鉴定

Anna Jirovec, Ashley Flaman, Elena Godbout, Daniel Serrano, Joel Werier, Bibianna Purgina, Jean-Simon Diallo

ENPP1 enzyme replacement therapy improves ectopic calcification but does not rescue skeletal phenotype in a mouse model for craniometaphyseal dysplasia.

ENPP1 酶替代疗法可改善异位钙化,但不能挽救颅骨干骺端发育不良小鼠模型的骨骼表型

Reichenberger Ernst J, O'Brien Kevin, Hatori Ayano, Carpenter Thomas O, van de Wetering Koen, Flaman Lisa, Howe Jennifer, Ortiz Daniel, Sabbagh Yves, Chen I-Ping

Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters

去除衰老细胞可降低 SARS-CoV-2 感染的老年仓鼠的病毒载量并减轻肺部和全身炎症

Lou Delval #, Aline Hantute-Ghesquier #, Valentin Sencio #, Jean Michel Flaman, Cyril Robil, Fabiola Silva Angulo, Larissa Lipskaia, Ozmen Çobanoğlu, Anne-Sophie Lacoste, Arnaud Machelart, Adeline Danneels, Mathieu Corbin, Lucie Deruyter, Séverine Heumel, Thierry Idziorek, Karin Séron, Florent Sauve

RSK3 switches cell fate: from stress-induced senescence to malignant progression

RSK3 改变细胞命运:从应激诱导的衰老到恶性进展

Anda Huna, Jean-Michel Flaman #, Catalina Lodillinsky #, Kexin Zhu, Gabriela Makulyte, Victoria Pakulska, Yohann Coute, Clémence Ruisseaux, Pierre Saintigny, Hector Hernandez-Vargas, Pierre-Antoine Defossez, Mathieu Boissan, Nadine Martin, David Bernard