日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Safety and efficacy of [(177)Lu]Lu-SibuDAB in patients with progressive metastatic castration-resistant prostate cancer

[(177)Lu]Lu-SibuDAB 在进展性转移性去势抵抗性前列腺癌患者中的安全性和有效性

Fernández, René; Soza-Ried, Cristian; Kramer, Vasko; Krieger, Korbinian; Müller, Cristina; Qin, Yun; Fliegert, Frank; Ritt, Philipp; Zhernosekov, Konstantin; Amaral, Horacio; Estay, Roberto; Nicolai, Heinz

Domain-Specific Agonist Binding Affinities Explain Structural and Functional Regulation of TRPM2

结构域特异性激动剂结合亲和力解释了TRPM2的结构和功能调控

Kupriianova, Tatiana; Schwarzer, Tessa; Thalacker, Thorben; Defelipe, Lucas; Etzold, Stefanie; Kulow, Frederike; Pahl, Vanessa; Goyal, Shivansh; Nguyen, Vanna; Zimmermann, Michael; Guse, Andreas H; Cambronne, Xiaolu A; Tidow, Henning; Fliegert, Ralf; Alai, Maria Garcia

2'-deoxy-ADPR activates human TRPM2 faster than ADPR and thereby induces higher currents at physiological Ca2+ concentrations

2'-脱氧-ADPR 比 ADPR 更快地激活人类 TRPM2,从而在生理 Ca2+ 浓度下诱导更高的电流

Jelena Pick, Simon Sander, Stefanie Etzold, Anette Rosche, Henning Tidow, Andreas H Guse, Ralf Fliegert

Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin

苦味受体 T2R14 在芹菜素诱导的延长存活时间和增强化学反应性中的潜在作用

Louisa Stern, Lukas Fabian Boehme, Mara Rebecca Goetz, Christine Nitschke, Anastasios Giannou, Tao Zhang, Cenap Güngör, Matthias Reeh, Jakob Robert Izbicki, Ralf Fliegert, Anne Hausen, Nathalia Giese, Thilo Hackert, Masha Y Niv, Stefan Heinrich, Matthias Martin Gaida #, Tarik Ghadban #

The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn2+ -binding domain essential for structural integrity and channel activity

TRPM2 MHR1/2结构域的晶体结构揭示了一个保守的Zn2+结合结构域,该结构域对于结构完整性和通道活性至关重要。

Simon Sander ,Jelena Pick ,Ellen Gattkowski ,Ralf Fliegert ,Henning Tidow

cADPR Does Not Activate TRPM2

cADPR 不激活 TRPM2

Winnie Maria Riekehr, Simon Sander, Jelena Pick, Henning Tidow, Andreas Bauche, Andreas H Guse, Ralf Fliegert

CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression

CD73 介导的 CD8 T 细胞衍生的细胞外囊泡产生腺苷是免疫抑制的内在机制

Enja Schneider #, Riekje Winzer #, Anne Rissiek, Isabell Ricklefs, Catherine Meyer-Schwesinger, Franz L Ricklefs, Andreas Bauche, Jochen Behrends, Rudolph Reimer, Santra Brenna, Hauke Wasielewski, Melchior Lauten, Björn Rissiek, Berta Puig, Filippo Cortesi, Tim Magnus, Ralf Fliegert, Christa E Mülle

Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9

焦磷酸酶 NUDT9 中配体结合及其导致的构象变化的分析

Ellen Gattkowski, Trevor J Rutherford, Franziska Möckl, Andreas Bauche, Simon Sander, Ralf Fliegert, Henning Tidow

Does Cyclic ADP-Ribose (cADPR) Activate the Non-selective Cation Channel TRPM2?

环状ADP-核糖(cADPR)是否能激活非选择性阳离子通道TRPM2?

Fliegert, Ralf; Riekehr, Winnie M; Guse, Andreas H

A structural overview of the ion channels of the TRPM family

TRPM家族离子通道的结构概述

Huang, Yihe; Fliegert, Ralf; Guse, Andreas H; Lü, Wei; Du, Juan