An oral non-covalent non-peptidic inhibitor of SARS-CoV-2 Mpro ameliorates viral replication and pathogenesis in vivo.
SARS-CoV-2 Mpro 的口服非共价非肽抑制剂可改善体内病毒复制和致病性
期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2024.114929
Zhou Nian E, Tang Su, Bian Xuelin, Parai Maloy K, Krieger Inna V, Flores Armando, Jaiswal Pradeep K, Bam Radha, Wood Jeremy L, Shi Zhe, Stevens Laura J, Scobey Trevor, Diefenbacher Meghan V, Moreira Fernando R, Baric Thomas J, Acharya Arjun, Shin Joonyoung, Rathi Manish M, Wolff Karen C, Riva Laura, Bakowski Malina A, McNamara Case W, Catanzaro Nicholas J, Graham Rachel L, Schultz David C, Cherry Sara, Kawaoka Yoshihiro, Halfmann Peter J, Baric Ralph S, Denison Mark R, Sheahan Timothy P, Sacchettini James C
