Florian Perrin相关文献与解析，生知库 | 链接生命科学的每一步

CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN 1 M146L mutation

CRISPR-Cas9 治疗可部分恢复携带阿尔茨海默病 PSEN 1 M146L 突变的人类成纤维细胞中的淀粉样蛋白 β42/40。

doi:10.1016/j.omtn.2022.03.022

Evangelos Konstantinidis ,Agnieszka Molisak ,Florian Perrin ,Linn Streubel-Gallasch ,Sarah Fayad ,Daniel Y Kim ,Karl Petri ,Martin J Aryee ,Ximena Aguilar ,Bence György ,Vilmantas Giedraitis ,J Keith Joung ,Vikram Pattanayak ,Magnus Essand ,Anna Erlandsson ,Oksana Berezovska ,Martin Ingelsson

Mechanism of Cellular Formation and In Vivo Seeding Effects of Hexameric β-Amyloid Assemblies

六聚体β-淀粉样蛋白组装体的细胞形成机制及其体内播种效应

期刊:Molecular Neurobiology

影响因子:4.6

doi:10.1007/s12035-021-02567-8

Céline Vrancx ，Devkee M Vadukul ，Nuria Suelves # ，Sabrina Contino # ，Ludovic D'Auria ，Florian Perrin ，Vincent van Pesch ，Bernard Hanseeuw ，Loïc Quinton ，Pascal Kienlen-Campard

细胞生物学

发表日期：2021

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Limited Substrate Specificity of PS/γ-Secretase Is Supported by Novel Multiplexed FRET Analysis in Live Cells

活细胞中新型多重 FRET 分析证实 PS/γ-分泌酶的有限底物特异性

期刊:Biosensors-Basel

影响因子:

doi:10.3390/bios11060169

Mei C Q Houser, Yuliia Turchyna, Florian Perrin, Lori Chibnik, Oksana Berezovska, Masato Maesako

The Interaction between Lockdown-Specific Conditions and Family-Specific Variables Explains the Presence of Child Insomnia during COVID-19: A Key Response to the Current Debate

封锁特定条件与家庭特定变量之间的相互作用解释了新冠疫情期间儿童失眠的出现：对当前争论的关键回应

期刊:International Journal of Environmental Research and Public Health

影响因子:

doi:10.3390/ijerph182312503

Anders, Royce; Lecuelle, Florian; Perrin, Clément; Ruyter, Swann; Franco, Patricia; Huguelet, Stéphanie; Putois, Benjamin

Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release

淀粉样蛋白前体 (APP) 控制转录激活因子神经元 PAS 结构域蛋白 4 (NPAS4) 的表达和突触 GABA 释放

期刊:eNeuro

影响因子:2.7

doi:10.1523/ENEURO.0322-19.2020

Rémi Opsomer, Sabrina Contino, Florian Perrin, Roberta Gualdani, Bernadette Tasiaux, Pierre Doyen, Maxime Vergouts, Céline Vrancx, Anna Doshina, Nathalie Pierrot, Jean-Noël Octave, Philippe Gailly, Serena Stanga, Pascal Kienlen-Campard

神经

发表日期：2020

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Glutamate Transporter 1 as a Novel Negative Regulator of Amyloid β

谷氨酸转运蛋白 1 作为淀粉样蛋白 β 的新型负向调节剂

Identification of PS1/gamma-secretase and glutamate transporter GLT-1 interaction sites

鉴定 PS1/γ-分泌酶和谷氨酸转运蛋白 GLT-1 相互作用位点

CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN 1 M146L mutation

CRISPR-Cas9 治疗可部分恢复携带阿尔茨海默病 PSEN 1 M146L 突变的人类成纤维细胞中的淀粉样蛋白 β42/40。

Mechanism of Cellular Formation and In Vivo Seeding Effects of Hexameric β-Amyloid Assemblies

六聚体β-淀粉样蛋白组装体的细胞形成机制及其体内播种效应

Limited Substrate Specificity of PS/γ-Secretase Is Supported by Novel Multiplexed FRET Analysis in Live Cells

活细胞中新型多重 FRET 分析证实 PS/γ-分泌酶的有限底物特异性

The Interaction between Lockdown-Specific Conditions and Family-Specific Variables Explains the Presence of Child Insomnia during COVID-19: A Key Response to the Current Debate

封锁特定条件与家庭特定变量之间的相互作用解释了新冠疫情期间儿童失眠的出现：对当前争论的关键回应

Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release

淀粉样蛋白前体 (APP) 控制转录激活因子神经元 PAS 结构域蛋白 4 (NPAS4) 的表达和突触 GABA 释放