Population-scale cellular GUIDE-seq-2 and biochemical CHANGE-seq-R profiles reveal human genetic variation frequently affects Cas9 off-target activity
群体规模的细胞 GUIDE-seq-2 和生化 CHANGE-seq-R 分析表明，人类遗传变异经常影响 Cas9 的脱靶活性。
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doi:10.1101/2025.02.10.637517
Lazzarotto, Cicera R; Li, Yichao; Flory, Ashley R; Chyr, Jacqueline; Yang, Muyu; Katta, Varun; Urbina, Elizabeth; Lee, GaHyun; Wood, Rachael; Matsubara, Azusa; Rashkin, Sara R; Ma, Jian; Cheng, Yong; Tsai, Shengdar Q
