Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target
优化TAM16（一种抑制Pks13硫酯酶活性的苯并呋喃类化合物）；评估其作为新型抗结核临床靶点的临床前候选药物
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.1c01586
Wilson, Caroline; Ray, Peter; Zuccotto, Fabio; Hernandez, Jorge; Aggarwal, Anup; Mackenzie, Claire; Caldwell, Nicola; Taylor, Malcolm; Huggett, Margaret; Mathieson, Michael; Murugesan, Dinakaran; Smith, Alasdair; Davis, Susan; Cocco, Mattia; Parai, Maloy K; Acharya, Arjun; Tamaki, Fabio; Scullion, Paul; Epemolu, Ola; Riley, Jennifer; Stojanovski, Laste; Lopez-Román, Eva Maria; Torres-Gómez, Pedro Alfonso; Toledo, Ana Maria; Guijarro-Lopez, Laura; Camino, Isabel; Engelhart, Curtis A; Schnappinger, Dirk; Massoudi, Lisa M; Lenaerts, Anne; Robertson, Gregory T; Walpole, Chris; Matthews, David; Floyd, David; Sacchettini, James C; Read, Kevin D; Encinas, Lourdes; Bates, Robert H; Green, Simon R; Wyatt, Paul G
