日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade

肠道微生物群特征与 CTLA-4 和 PD-1 联合阻断的毒性相关

Miles C Andrews #, Connie P M Duong #, Vancheswaran Gopalakrishnan #, Valerio Iebba #, Wei-Shen Chen #, Lisa Derosa #, Md Abdul Wadud Khan, Alexandria P Cogdill, Michael G White, Matthew C Wong, Gladys Ferrere, Aurélie Fluckiger, Maria P Roberti, Paule Opolon, Maryam Tidjani Alou, Satoru Yonekura, W

Multifaceted modes of action of the anticancer probiotic Enterococcus hirae

抗癌益生菌粪肠球菌的多重作用机制

Anne-Gaëlle Goubet # ,Richard Wheeler # ,Aurélie Fluckiger ,Bo Qu ,Fabien Lemaître ,Kristina Iribarren ,Laura Mondragón ,Maryam Tidjani Alou ,Eugénie Pizzato ,Sylvère Durand ,Lisa Derosa ,Fanny Aprahamian ,Noélie Bossut ,Maryse Moya-Nilges ,Diane Derrien ,Guo Chen ,Marion Leduc ,Adrien Joseph ,Nicolas Pons ,Emmanuelle Le Chatelier ,Nicola Segata ,Satoru Yonekura ,Valerio Iebba ,Oliver Kepp ,Didier Raoult ,Fabrice André ,Guido Kroemer ,Ivo Gomperts Boneca ,Laurence Zitvogel ,Romain Daillère

Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade

生酮饮食和酮体可增强PD-1阻断的抗癌作用

Gladys Ferrere ,Maryam Tidjani Alou ,Peng Liu ,Anne-Gaëlle Goubet ,Marine Fidelle ,Oliver Kepp ,Sylvère Durand ,Valerio Iebba ,Aurélie Fluckiger ,Romain Daillère ,Cassandra Thelemaque ,Claudia Grajeda-Iglesias ,Carolina Alves Costa Silva ,Fanny Aprahamian ,Déborah Lefevre ,Liwei Zhao ,Bernhard Ryffel ,Emeline Colomba ,Monica Arnedos ,Damien Drubay ,Conrad Rauber ,Didier Raoult ,Francesco Asnicar ,Tim Spector ,Nicola Segata ,Lisa Derosa ,Guido Kroemer ,Laurence Zitvogel

An enveloped virus-like particle vaccine expressing a stabilized prefusion form of the SARS-CoV-2 spike protein elicits highly potent immunity.

表达SARS-CoV-2刺突蛋白稳定融合前形式的包膜病毒样颗粒疫苗可诱导产生高度有效的免疫力

Fluckiger Anne-Catherine, Ontsouka Barthelemy, Bozic Jasminka, Diress Abebaw, Ahmed Tanvir, Berthoud Tamara, Tran Anh, Duque Diane, Liao Mingmin, McCluskie Michael, Diaz-Mitoma Francisco, Anderson David E, Soare Catalina

Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

化疗诱导的回肠隐窝细胞凋亡和回肠微生物群形成近端结肠癌的免疫监视和预后

Maria Paula Roberti, Satoru Yonekura, Connie P M Duong, Marion Picard, Gladys Ferrere, Maryam Tidjani Alou, Conrad Rauber, Valerio Iebba, Christian H K Lehmann, Lukas Amon, Diana Dudziak, Lisa Derosa, Bertrand Routy, Caroline Flament, Corentin Richard, Romain Daillère, Aurélie Fluckiger, Isabelle Va

Elucidating the gut microbiota composition and the bioactivity of immunostimulatory commensals for the optimization of immune checkpoint inhibitors

阐明肠道菌群组成和免疫刺激共生菌的生物活性,以优化免疫检查点抑制剂

Daillère, Romain; Routy, Bertrand; Goubet, Anne-Gaëlle; Cogdill, Alexandria; Ferrere, Gladys; Alves-Costa Silva, Carolina; Fluckiger, Aurélie; Ly, Pierre; Haddad, Yacine; Pizzato, Eugenie; Thelemaque, Cassandra; Fidelle, Marine; Mazzenga, Marine; Roberti, Maria Paula; Melenotte, Cléa; Liu, Peng; Terrisse, Safae; Kepp, Oliver; Kroemer, Guido; Zitvogel, Laurence; Derosa, Lisa

[Clinical trials during pandemic crisis: How to ensure safety and maintain access to innovation]

【疫情危机期间的临床试验:如何确保安全并维持创新成果的获取】

Vignot, Stéphane; Le Blaye, Olivier; Fluckiger, Laurence; Errard, Sonia; Marin, Benoît; Chapel, Elodie

T-cell bispecific antibodies in node-positive breast cancer: novel therapeutic avenue for MHC class I loss variants

T细胞双特异性抗体在淋巴结阳性乳腺癌中的应用:MHC I类缺失变异体的新治疗途径

Messaoudene, M; Mourikis, T P; Michels, J; Fu, Y; Bonvalet, M; Lacroix-Trikki, M; Routy, B; Fluckiger, A; Rusakiewicz, S; Roberti, M P; Cotteret, S; Flament, C; Poirier-Colame, V; Jacquelot, N; Ghiringhelli, F; Caignard, A; Eggermont, A M M; Kroemer, G; Marabelle, A; Arnedos, M; Vicier, C; Dogan, S; Jaulin, F; Sammut, S-J; Cope, W; Caldas, C; Delaloge, S; McGranahan, N; André, F; Zitvogel, L

Docosahexaenoic acid inhibits both NLRP3 inflammasome assembly and JNK-mediated mature IL-1β secretion in 5-fluorouracil-treated MDSC: implication in cancer treatment

二十二碳六烯酸抑制 5-氟尿嘧啶处理的 MDSC 中的 NLRP3 炎症小体组装和 JNK 介导的成熟 IL-1β 分泌:对癌症治疗的意义

Adélie Dumont, Charlotte de Rosny, Trinh-Le-Vi Kieu, Sabrina Perrey, Hélène Berger, Aurélie Fluckiger, Tania Muller, Jean-Paul Pais de Barros, Laurent Pichon, Aziz Hichami, Charles Thomas, Cédric Rébé, François Ghiringhelli, Mickaël Rialland

An empirical method for reducing variability and complexity of myocardial perfusion quantification by dual bolus cardiac MRI

一种通过双推注心脏磁共振成像降低心肌灌注定量分析变异性和复杂性的经验方法

Chatterjee, Neil; Benefield, Brandon C; Harris, Kathleen R; Fluckiger, Jacob U; Carroll, Timothy; Lee, Daniel C