日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

High-dimensional temporal mapping of CAR T cells reveals phenotypic and functional remodeling during manufacturing

对CAR-T细胞进行高维时间映射,揭示了其在生产过程中的表型和功能重塑。

Cadinanos-Garai, Amaia; Flugel, Christian L; Cheung, Anson; Jiang, Enzi; Vaissié, Alix; Abou-El-Enein, Mohamed

Author Correction: Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells

作者更正:结合使用不同的 CRISPR 核酸酶进行同步基因敲入和碱基编辑可防止多重编辑的 CAR T 细胞发生易位。

Glaser, Viktor; Flugel, Christian; Kath, Jonas; Du, Weijie; Drosdek, Vanessa; Franke, Clemens; Stein, Maik; Pruß, Axel; Schmueck-Henneresse, Michael; Volk, Hans-Dieter; Reinke, Petra; Wagner, Dimitrios L

Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours

克服CAR-T细胞疗法治疗实体瘤的靶向毒性和脱靶毒性

Flugel, Christian L; Majzner, Robbie G; Krenciute, Giedre; Dotti, Gianpietro; Riddell, Stanley R; Wagner, Dimitrios L; Abou-El-Enein, Mohamed

Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells

将不同的 CRISPR 核酸酶结合使用,可同时进行基因敲入和碱基编辑,从而防止多重编辑的 CAR-T 细胞发生易位。

Viktor Glaser ,Christian Flugel ,Jonas Kath ,Weijie Du ,Vanessa Drosdek ,Clemens Franke ,Maik Stein ,Axel Pruß ,Michael Schmueck-Henneresse ,Hans-Dieter Volk ,Petra Reinke ,Dimitrios L Wagner

Bringing base editing to the clinic: The next generation of genome editors

将碱基编辑技术应用于临床:下一代基因组编辑器

Flugel, Christian L; Abou-El-Enein, Mohamed

Cost-Benefit and Cost-Effectiveness Analysis in Health Care: Principles, Practice, and Potential

医疗保健中的成本效益分析:原则、实践和潜力

Schmidt, Charles W; Flugel, J C; Showstack, Jonathan A