日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Using Data Science for Mechanistic Insights and Selectivity Predictions in a Non-Natural Biocatalytic Reaction

利用数据科学进行非天然生物催化反应的机理分析和选择性预测

Clements, Hanna D; Flynn, Autumn R; Nicholls, Bryce T; Grosheva, Daria; Lefave, Sarah J; Merriman, Morgan T; Hyster, Todd K; Sigman, Matthew S

Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators

SF-1和LRH-1与小分子调节剂复合物的活性、结构和动力学比较

Cato, Michael L; D'Agostino, Emma H; Spurlin, Racheal M; Flynn, Autumn R; Cornelison, Jeffery L; Johnson, Alyssa M; Fujita, Rei A; Abraham, Sarah M; Jui, Nathan T; Ortlund, Eric A

Data Science-Driven Analysis of Substrate-Permissive Diketopiperazine Reverse Prenyltransferase NotF: Applications in Protein Engineering and Cascade Biocatalytic Synthesis of (-)-Eurotiumin A

基于数据科学的底物容许性二酮哌嗪逆异戊二烯基转移酶 NotF 分析:在蛋白质工程和 (-)-Eurotiumin A 级联生物催化合成中的应用

Kelly, Samantha P; Shende, Vikram V; Flynn, Autumn R; Dan, Qingyun; Ye, Ying; Smith, Janet L; Tsukamoto, Sachiko; Sigman, Matthew S; Sherman, David H

Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket

通过靶向结合口袋的埋藏区域和表面区域来差异性调节核受体LRH-1

Cato, Michael L; Cornelison, Jeffery L; Spurlin, Racheal M; Courouble, Valentine V; Patel, Anamika B; Flynn, Autumn R; Johnson, Alyssa M; Okafor, C Denise; Frank, Filipp; D'Agostino, Emma H; Griffin, Patrick R; Jui, Nathan T; Ortlund, Eric A

Hydroarylation of Arenes via Reductive Radical-Polar Crossover

芳烃的还原自由基-极性交叉氢芳基化

Flynn, Autumn R; McDaniel, Kelly A; Hughes, Meredith E; Vogt, David B; Jui, Nathan T

Development of the First Low Nanomolar Liver Receptor Homolog-1 Agonist through Structure-guided Design.

通过结构导向设计开发首个低纳摩尔肝受体同源物-1激动剂

Mays Suzanne G, Flynn Autumn R, Cornelison Jeffery L, Okafor C Denise, Wang Hongtao, Wang Guohui, Huang Xiangsheng, Donaldson Heather N, Millings Elizabeth J, Polavarapu Rohini, Moore David D, Calvert John W, Jui Nathan T, Ortlund Eric A