Flynn Rowan相关文献与解析，生知库 | 链接生命科学的每一步

Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons

α-突触核蛋白诱导帕金森病SNCA三倍体iPSC衍生神经元中的未折叠蛋白反应

Heman-Ackah, Sabrina M; Manzano, Raquel; Hoozemans, Jeroen J M; Scheper, Wiep; Flynn, Rowan; Haerty, Wilfried; Cowley, Sally A; Bassett, Andrew R; Wood, Matthew J A

帕金森

神经科学

发表日期：2017

文献求助收藏

CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells

利用 CRISPR 介导的人类 iPS 细胞中慢性肉芽肿病突变的基因型和表型校正

期刊:Experimental Hematology

影响因子:2.1

doi:10.1016/j.exphem.2015.06.002

Flynn, Rowan; Grundmann, Alexander; Renz, Peter; Hänseler, Walther; James, William S; Cowley, Sally A; Moore, Michael D

Improved animal models for testing gene therapy for atherosclerosis

改进的动物模型用于测试动脉粥样硬化基因疗法

期刊:Human Gene Therapy Methods

影响因子:

doi:10.1089/hgtb.2013.199

Du, Liang; Zhang, Jingwan; De Meyer, Guido R Y; Flynn, Rowan; Dichek, David A

Correction of the ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Gene by Zinc-Finger Nuclease Homology-Directed Repair

利用锌指核酸酶同源定向修复法纠正囊性纤维化跨膜传导调节因子基因中的ΔF508突变

期刊:

影响因子:

doi:10.1089/biores.2012.0218

Lee, Ciaran M; Flynn, Rowan; Hollywood, Jennifer A; Scallan, Martina F; Harrison, Patrick T

发表日期：2012

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Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis

兔颈动脉内皮细胞中载脂蛋白AI的表达可预防动脉粥样硬化

期刊:Molecular Therapy

影响因子:12

doi:10.1038/mt.2011.133

Flynn, Rowan; Qian, Kun; Tang, Chongren; Dronadula, Nagadhara; Buckler, Joshua M; Jiang, Bo; Wen, Shan; Dichek, Helén L; Dichek, David A

Helper-dependent adenoviral vectors are superior in vitro to first-generation vectors for endothelial cell-targeted gene therapy

辅助依赖型腺病毒载体在体外内皮细胞靶向基因治疗方面优于第一代载体。

期刊:Molecular Therapy

影响因子:12

doi:10.1038/mt.2010.176

Flynn, Rowan; Buckler, Joshua M; Tang, Chongren; Kim, Francis; Dichek, David A

Profiling of naÃ¯ve and primed human pluripotent stem cells reveals state-associated miRNAs.

对幼稚和启动的人类多能干细胞进行分析，揭示了与状态相关的 miRNA

Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons

α-突触核蛋白诱导帕金森病SNCA三倍体iPSC衍生神经元中的未折叠蛋白反应

CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells

利用 CRISPR 介导的人类 iPS 细胞中慢性肉芽肿病突变的基因型和表型校正

Improved animal models for testing gene therapy for atherosclerosis

改进的动物模型用于测试动脉粥样硬化基因疗法

Correction of the ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Gene by Zinc-Finger Nuclease Homology-Directed Repair

利用锌指核酸酶同源定向修复法纠正囊性纤维化跨膜传导调节因子基因中的ΔF508突变

Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis

兔颈动脉内皮细胞中载脂蛋白AI的表达可预防动脉粥样硬化

Helper-dependent adenoviral vectors are superior in vitro to first-generation vectors for endothelial cell-targeted gene therapy

辅助依赖型腺病毒载体在体外内皮细胞靶向基因治疗方面优于第一代载体。