日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

TG6002 oncolytic vaccinia virus and chemotherapy synergy: a promising strategy for pancreatic ductal adenocarcinoma

TG6002溶瘤痘苗病毒与化疗的协同作用：胰腺导管腺癌的一种有前景的治疗策略

期刊:Frontiers in Microbiology
影响因子:4.5
doi:10.3389/fmicb.2025.1656984
Foloppe, Johann; Farine, Isabelle; Pichon, Christelle; Kempf, Juliette; Hortelano, Julie; Moreau, Baptiste; Cochin, Sandrine; Takeda, Armelle; Pessaux, Patrick; Erbs, Philippe
微生物学
肿瘤
肿瘤免疫
发表日期：2025
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TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody, favors tumor regression via profound immune remodeling of the tumor microenvironment

TG6050是一种溶瘤痘苗病毒，编码白细胞介素-12和抗CTLA-4抗体，它通过对肿瘤微环境进行深刻的免疫重塑来促进肿瘤消退。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-009302
Azar, Fadi; Deforges, Jules; Demeusoit, Christelle; Kleinpeter, Patricia; Remy, Christelle; Silvestre, Nathalie; Foloppe, Johann; Fend, Laetitia; Spring-Giusti, Clémentine; Quéméneur, Eric; Marchand, Jean-Baptiste
肿瘤
肿瘤免疫
微生物学
细胞生物学
肿瘤微环境
免疫/内分泌
发表日期：2024
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Mediation of antitumor activity by AZD4820 oncolytic vaccinia virus encoding IL-12

编码 IL-12 的 AZD4820 溶瘤痘苗病毒介导抗肿瘤活性

期刊:Molecular Therapy Oncology
影响因子:4.5
doi:10.1016/j.omton.2023.200758
Cheyne Kurokawa, Sonia Agrawal, Abhisek Mitra, Elena Galvani, Shannon Burke, Ankita Varshine, Raymond Rothstein, Kevin Schifferli, Noel R Monks, Johann Foloppe, Nathalie Silvestre, Eric Quemeneur, Christelle Demeusoit, Patricia Kleinpeter, Puja Sapra, Carl Barrett, Scott A Hammond, Elizabeth J Kelly
信号转导
微生物学
肿瘤
MSD
Mouse
IL12A
IL12B
发表日期：2024
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Oncolytic virotherapy with intratumoral injection of vaccinia virus TG6002 and 5-fluorocytosine administration in dogs with malignant tumors

瘤内注射痘苗病毒 TG6002 和给予 5-氟胞嘧啶对患有恶性肿瘤的狗进行溶瘤病毒治疗

期刊:Molecular Therapy-Oncolytics
影响因子:5.3
doi:10.1016/j.omto.2023.07.005
Jérémy Béguin, Eve Laloy, Sandrine Cochin, Murielle Gantzer, Isabelle Farine, Christelle Pichon, Baptiste Moreau, Johann Foloppe, Jean-Marc Balloul, Christelle Machon, Jérôme Guitton, Dominique Tierny, Bernard Klonjkowski, Eric Quéméneur, Christelle Maurey, Philippe Erbs
微生物学
肿瘤
发表日期：2023
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Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8(+) T cell immunity to reject 'cold' tumors

载体化的Treg细胞清除剂αCTLA-4可诱导抗原交叉呈递和CD8(+) T细胞免疫，从而排斥“冷”肿瘤

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2021-003488
Semmrich, Monika; Marchand, Jean-Baptiste; Fend, Laetitia; Rehn, Matilda; Remy, Christelle; Holmkvist, Petra; Silvestre, Nathalie; Svensson, Carolin; Kleinpeter, Patricia; Deforges, Jules; Junghus, Fred; Cleary, Kirstie L; Bodén, Mimoza; Mårtensson, Linda; Foloppe, Johann; Teige, Ingrid; Quéméneur, Eric; Frendéus, Björn
肿瘤
T细胞
肿瘤免疫
CD8
Treg
T细胞
细胞生物学
免疫/内分泌
发表日期：2022
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Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B

片段衍生的双特异性激酶 DYRK1A 和 DYRK1B 选择性抑制剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.1c00024
David Lee Walmsley, James B Murray, Pawel Dokurno, Andrew J Massey, Karen Benwell, Andrea Fiumana, Nicolas Foloppe, Stuart Ray, Julia Smith, Allan E Surgenor, Thomas Edmonds, Didier Demarles, Mike Burbridge, Francisco Cruzalegui, Andras Kotschy, Roderick E Hubbard
信号转导
发表日期：2021
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The future of biomolecular simulation in the pharmaceutical industry: what we can learn from aerodynamics modelling and weather prediction. Part 1. understanding the physical and computational complexity of in silico drug design

生物分子模拟在制药行业的未来：我们可以从空气动力学建模和天气预报中学到什么。第一部分：理解计算机辅助药物设计的物理和计算复杂性

期刊:Acta Crystallographica Section D-Structural Biology
影响因子:3.8
doi:10.1107/S2059798321009712
Edwards, Tom; Foloppe, Nicolas; Harris, Sarah Anne; Wells, Geoff
发表日期：2021
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High Oncolytic Activity of a Double-Deleted Vaccinia Virus Copenhagen Strain against Malignant Pleural Mesothelioma

双缺失痘苗病毒哥本哈根株对恶性胸膜间皮瘤具有高溶瘤活性

期刊:Molecular Therapy-Oncolytics
影响因子:5.3
doi:10.1016/j.omto.2020.08.011
Delaunay, Tiphaine; Nader, Joelle; Grard, Marion; Farine, Isabelle; Hedwig, Vera; Foloppe, Johann; Blondy, Thibaut; Violland, Mathilde; Pouliquen, Daniel; Grégoire, Marc; Boisgerault, Nicolas; Erbs, Philippe; Fonteneau, Jean-François
微生物学
发表日期：2020
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Preclinical Evaluation of the Oncolytic Vaccinia Virus TG6002 by Translational Research on Canine Breast Cancer

通过犬乳腺癌转化研究对溶瘤痘苗病毒 TG6002 进行临床前评估

期刊:Molecular Therapy-Oncolytics
影响因子:5.3
doi:10.1016/j.omto.2020.08.020
Jérémy Béguin, Johann Foloppe, Christelle Maurey, Eve Laloy, Julie Hortelano, Virginie Nourtier, Christelle Pichon, Sandrine Cochin, Pascale Cordier, Hélène Huet, Eric Quemeneur, Bernard Klonjkowski, Philippe Erbs
信号转导
微生物学
肿瘤
乳腺癌
Translational Control
Canine
发表日期：2020
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Fluorescent Tagged Vaccinia Virus Genome Allows Rapid and Efficient Measurement of Oncolytic Potential and Discovery of Oncolytic Modulators

荧光标记的痘苗病毒基因组可以快速有效地测量溶瘤潜力并发现溶瘤调节剂

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines8120543
Franck Gallardo, Doris Schmitt, Renée Brandely, Catherine Brua, Nathalie Silvestre, Annie Findeli, Johann Foloppe, Sokunthea Top, Sandrine Kappler-Gratias, Charlotte Quentin-Froignant, Renaud Morin, Jean-Michel Lagarde, Kerstin Bystricky, Stéphane Bertagnoli, Philippe Erbs
微生物学
肿瘤
FCM
IF
IHC-P
WB
发表日期：2020
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