日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functionally heterogeneous intratumoral CD4(+)CD8(+) double-positive T cells can give rise to single-positive T cells

功能异质性的肿瘤内CD4(+)CD8(+)双阳性T细胞可以分化为单阳性T细胞。

Li, Tony; Ilano, Arielle; Arias-Badia, Marcel; Luong, Diamond; Chang, Hewitt; Kwek, Serena S; Allaire, Kathryn; Chumber, Arun; Sakamoto, Mason; Clark, Matthew; Lea, Averey; Bridge, Mark; Chen, Brandon; Liu, Eric; Porten, Sima; Meng, Maxwell V; Erlich, Lauren I R; Oh, David Y; Fong, Lawrence

Phase II trial with nivolumab and sorafenib in HCC identified enrichment of immunosuppressive monocytes in patients with Child-Pugh B liver dysfunction

一项针对肝细胞癌患者的II期临床试验(使用纳武利尤单抗联合索拉非尼)发现,Child-Pugh B级肝功能障碍患者体内免疫抑制性单核细胞富集。

Keenan, Bridget P; Fan, Zenghua; Le, Bryan Khuong; Harris, Quincy; Chen, Jocelin; Clark, Matthew; Lea, Averey; Zhang, Li; Cheung, Alexander; Lara, Frances; Gordan, John D; Bracci, Paige; Behr, Spencer C; Fong, Lawrence; Venook, Alan P; Kim, Edward J; Kelley, Robin K

Supporting safe walking and managing missing incidents in dementia: a qualitative narrative synthesis of current evidence

支持痴呆症患者安全行走和管理走失事件:现有证据的定性叙述性综合分析

Kwok, Hoi Tat; Dhawan, Annika; Lye, Valerie; Fong, Lawrence; Leung, Phuong; Orgeta, Vasiliki

Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial

Autogene cevumeran联合或不联合atezolizumab治疗晚期实体瘤:一项I期试验

Lopez, Juanita; Powles, Thomas; Braiteh, Fadi; Siu, Lillian L; LoRusso, Patricia; Friedman, Claire F; Balmanoukian, Ani S; Gordon, Michael; Yachnin, Jeffrey; Rottey, Sylvie; Karydis, Ioannis; Fisher, George A; Schmidt, Marcus; Schuler, Martin; Sullivan, Ryan J; Burris, Howard A; Galvao, Vladimir; Henick, Brian S; Dirix, Luc; Jaeger, Dirk; Ott, Patrick A; Wong, Kit Man; Jerusalem, Guy; Schiza, Aglaia; Fong, Lawrence; Steeghs, Neeltje; Leidner, Rom S; Rittmeyer, Achim; Laurie, Scott A; Gort, Eelke; Aljumaily, Raid; Melero, Ignacio; Sabado, Rachel L; Rhee, Ina; Mancuso, Michael R; Muller, Lars; Fine, Gregg D; Yadav, Mahesh; Kim, Leesun; Leveque, Vincent J P; Robert, Alberto; Darwish, Martine; Qi, Ting; Zhu, Jiawen; Zhang, Jingbin; Twomey, Patrick; Rao, Gautham K; Low, Donald W; Petry, Chris; Lo, Amy A; Schartner, Jill M; Delamarre, Lélia; Mellman, Ira; Löwer, Martin; Müller, Felicitas; Derhovanessian, Evelyna; Cortini, Andrea; Manning, Luisa; Maurus, Daniel; Brachtendorf, Sebastian; Lörks, Verena; Omokoko, Tana; Godehardt, Eva; Becker, Dirk; Hawner, Christine; Wallrapp, Christine; Albrecht, Christian; Kröner, Christoph; Tadmor, Arbel D; Diekmann, Jan; Vormehr, Mathias; Jork, Anette; Paruzynski, Anna; Lang, Maren; Blake, Jonathon; Hennig, Oliver; Kuhn, Andreas N; Sahin, Ugur; Türeci, Özlem; Camidge, D Ross

Phase I, First-in-Human Study of FOR46 (FG-3246), an Immune-Modulating Antibody-Drug Conjugate Targeting CD46, in Patients With Metastatic Castration-Resistant Prostate Cancer

FOR46 (FG-3246) 是一种靶向 CD46 的免疫调节抗体药物偶联物,用于治疗转移性去势抵抗性前列腺癌患者,这是一项 I 期首次人体研究。

Aggarwal, Rahul R; Vuky, Jacqueline; VanderWeele, David; Rettig, Matthew; Heath, Elisabeth I; Quigley, David; Huang, Jiaoti; Chumber, Arun; Cheung, Alexander; Foye, Adam; Leung, Stanley; Abbey, Jill; Dorr, Andrew; Nasoff, Marc; Hunter, John; Wang, Steven; Flavell, Robert R; Fong, Lawrence; Liu, Bin; Small, Eric J

Proceedings of the National Cancer Institute Workshop on combining immunotherapy with radiotherapy: challenges and opportunities for clinical translation

美国国家癌症研究所关于免疫疗法与放射疗法联合应用的研讨会论文集:临床转化的挑战与机遇

Morris, Zachary S; Demaria, Sandra; Monjazeb, Arta M; Formenti, Silvia C; Weichselbaum, Ralph R; Welsh, James; Enderling, Heiko; Schoenfeld, Jonathan D; Brody, Joshua D; McGee, Heather M; Mondini, Michele; Kent, Michael S; Young, Kristina H; Galluzzi, Lorenzo; Karam, Sana D; Theelen, Willemijn S M E; Chang, Joe Y; Huynh, Mai Anh; Daib, Adi; Pitroda, Sean; Chung, Caroline; Serre, Raphael; Grassberger, Clemens; Deng, Jie; Sodji, Quaovi H; Nguyen, Anthony T; Patel, Ravi B; Krebs, Simone; Kalbasi, Anusha; Kerr, Caroline; Vanpouille-Box, Claire; Vick, Logan; Aguilera, Todd A; Ong, Irene M; Herrera, Fernanda; Menon, Hari; Smart, DeeDee; Ahmed, Jalal; Gartrell, Robyn D; Roland, Christina L; Fekrmandi, Fatemeh; Chakraborty, Binita; Bent, Eric H; Berg, Tracy J; Hutson, Alan; Khleif, Samir; Sikora, Andrew G; Fong, Lawrence

Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics

通过临床单细胞转录组学中的群体生物学估计来解析肿瘤细胞程序

Johri, Shreya; Bi, Kevin; Titchen, Breanna M; Fu, Jingxin; Conway, Jake; Crowdis, Jett P; Vokes, Natalie I; Fan, Zenghua; Fong, Lawrence; Park, Jihye; Liu, David; He, Meng Xiao; Van Allen, Eliezer M

Combination LIGHT overexpression and checkpoint blockade disrupts the tumor immune environment impacting colorectal liver metastases.

LIGHT 过表达与检查点阻断相结合会破坏肿瘤免疫环境,从而影响结直肠肝转移。

Keenan Bridget P, Qiao Guilin, Kunda Nicholas, Kone Lyonell, Guldberg Sophia M, Todeschini Letizia, Kumar Prabhakaran, Pollini Tommaso, Hernandez Sophia, Qin Jianzhong, Fong Lawrence, Spitzer Matthew H, Prabhakar Bellur S, Maker Ajay V

Tumor cell heterogeneity drives spatial organization of the intratumoral immune response.

肿瘤细胞异质性驱动肿瘤内免疫反应的空间组织

Tanaka Miho, Lum Lotus, Hu Kenneth H, Chaudhary Piyush, Hughes Savannah, Ledezma-Soto Cecilia, Samad Bushra, Superville Daphne, Ng Kenneth, Chumber Arun, Benson Ciara, Adams Zoe N, Kersten Kelly, Aguilar Oscar A, Fong Lawrence, Combes Alexis J, Krummel Matthew F, Reeves Melissa Q

Clinical and Translational Results from PORTER, a Multicohort Phase I Platform Trial of Combination Immunotherapy in Metastatic Castration-Resistant Prostate Cancer

PORTER研究的临床和转化结果:一项针对转移性去势抵抗性前列腺癌的联合免疫疗法多队列I期平台试验

Galsky, Matthew D; Autio, Karen A; Cabanski, Christopher R; Wentzel, Kristopher; Graff, Julie N; Friedlander, Terence W; Howes, Timothy R; Shotts, Kristin M; Densmore, Julie; Spasic, Marko; Da Silva, Diane M; Chen, Richard O; Lata, Jennifer; Skolnik, Jeffrey; Keler, Tibor; Yellin, Michael J; LaVallee, Theresa M; Fairchild, Justin; Boffo, Silvia; O'Donnell-Tormey, Jill; Dugan, Ute; Bhardwaj, Nina; Subudhi, Sumit K; Fong, Lawrence