Foord相关文献与解析，生知库 | 链接生命科学的每一步

Combined single-cell profiling of chromatin-transcriptome and splicing across brain cell types, regions and disease state

结合单细胞染色质-转录组和剪接分析，研究脑细胞类型、区域和疾病状态下的染色质-转录组和剪接情况。

Wen Hu # ,Careen Foord # ,Justine Hsu # ,Li Fan ,Michael J Corley ,Samantha N Lanjewar ,Siwei Xu ,Natan Belchikov ,Yi He ,Alina P S Pang ,Tarun N Bhatia ,Julien Jarroux ,Anoushka Joglekar ,Teresa A Milner ,Lishomwa C Ndhlovu ,Jing Zhang ,Eduardo Butelman ,Steven A Sloan ,Virginia M Y Lee ,Li Gan ,Hagen U Tilgner

神经科学

A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types

接近单细胞分辨率的空间长读长测序方法揭示了不同皮层层级和细胞类型中剪接和多聚腺苷酸化位点的发育调控

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-63301-9

Careen Foord # ,Andrey D Prjibelski # ,Wen Hu # ,Lieke Michielsen ,Andrea Vandelli ,Oleksandr Narykov ,Brian Evans ,Justine Hsu ,Natan Belchikov ,Julien Jarroux ,Yi He ,M Elizabeth Ross ,Iman Hajirasouliha ,Gian Gaetano Tartaglia ,Dmitry Korkin ,Alexandru I Tomescu ,Hagen U Tilgner

Next-generation sequencing for guiding matched targeted therapies in people with relapsed or metastatic cancer

利用新一代测序技术指导复发或转移性癌症患者的靶向治疗

期刊:Cochrane Database of Systematic Reviews

影响因子:9.4

doi:10.1002/14651858.CD014872.pub2

Kazmi, Farasat; Shrestha, Nipun; Liu, Tik Fung Dave; Foord, Thomas; Heesen, Philip; Booth, Stephen; Dodwell, David; Lord, Simon; Yeoh, Kheng-Wei; Blagden, Sarah P

A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain

一项基于单细胞、长读长、亚型解析的FTD病例对照研究揭示了人脑中细胞类型特异性和广泛的剪接失调。

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2025.116198.

Natan Belchikov ,Wen Hu ,Li Fan ,Anoushka Joglekar ,Yi He ,Careen Foord ,Julien Jarroux ,Justine Hsu ,Shaun Pollard ,Sadaf Amin ,Andrey D Prjibelski ,Shiaoching Gong ,Sai Zhang ,Roberta Giannelli ,Harro Seelaar ,Alexandru I Tomescu ,M Elizabeth Ross ,Alissa Nana Li ,Lea T Grinberg ,Salvatore Spina ,Bruce L Miller ,Johnathan Cooper-Knock ,Michael P Snyder ,William W Seeley ,Priyanka Rao-Ruiz ,Sabine Spijker ,August B Smit ,Claire D Clelland ,Li Gan ,Hagen U Tilgner

Development and characterisation of a fully recombinant competition ELISA for the diagnosis of foot-and-mouth disease virus infection

开发和表征用于诊断口蹄疫病毒感染的全重组竞争性ELISA

期刊:Australian Veterinary Journal

影响因子:1.7

doi:10.1111/avj.13467

Ye, S; Balasubramanian, N S; Dolezal, O; Foord, A; Beddome, G; Michalski, W P; Shiell, B J; Peck, G R

A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types.

接近单细胞分辨率的空间长读长方法揭示了不同皮层层和细胞类型中剪接和多聚腺苷酸化位点的发育调控

期刊:

影响因子:

doi:10.1101/2025.06.10.658877

Foord Careen, Prjibelski Andrey D, Hu Wen, Michielsen Lieke, Vandelli Andrea, Narykov Oleksandr, Evans Brian, Hsu Justine, Belchikov Natan, Jarroux Julien, He Yi, Ross M Elizabeth, Hajirasouliha Iman, Tartaglia Gian Gaetano, Korkin Dmitry, Tomescu Alexandru I, Tilgner Hagen U

细胞生物学

发表日期：2025

文献求助收藏

Spatial isoform sequencing at sub-micrometer single-cell resolution reveals novel patterns of spatial isoform variability in brain cell types.

亚微米单细胞分辨率的空间同工型测序揭示了脑细胞类型中空间同工型变异的新模式

期刊:

影响因子:

doi:10.1101/2025.06.25.661563

Michielsen Lieke, Prjibelski Andrey, Foord Careen, Hu Wen, Jarroux Julien, Hsu Justine, Tomescu Alexandru, Hajirasouliha Iman, Tilgner Hagen

Elevating levels of the endocannabinoid 2-arachidonoylglycerol blunts opioid reward but not analgesia

提高内源性大麻素 2-花生四烯酸甘油酯的水平会减弱阿片类药物的奖赏效应，但不会减弱其镇痛作用。

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.adq4779

Martínez-Rivera, Arlene; Fetcho, Robert N; Birmingham, Lizzie; Xu, Jin; Yang, Ruirong; Foord, Careen; Scala-Chávez, Diego; Mekawy, Narmin; Pleil, Kristen; Pickel, Virginia M; Liston, Conor; Castorena, Carlos M; Levitz, Joshua; Pan, Ying-Xian; Briand, Lisa A; Rajadhyaksha, Anjali M; Lee, Francis S

发表日期：2024

文献求助收藏

Inducing expression of ICOS-L by oncolytic adenovirus to enhance tumor-specific bi-specific antibody efficacy

溶瘤腺病毒诱导ICOS-L表达增强肿瘤特异性双特异性抗体疗效

期刊:Journal of Translational Medicine

影响因子:6.1

doi:10.1186/s12967-024-05049-2

Neshat Saffarzadeh, Emelie Foord, Eoghan O'Leary, Rand Mahmoun, Thomas Birkballe Hansen, Victor Levitsky, Thomas Poiret #, Michael Uhlin #

Advances in donor-derived cell-free DNA monitoring for solid organ transplantation

供体来源的游离DNA监测在实体器官移植中的应用进展

Combined single-cell profiling of chromatin-transcriptome and splicing across brain cell types, regions and disease state

结合单细胞染色质-转录组和剪接分析，研究脑细胞类型、区域和疾病状态下的染色质-转录组和剪接情况。

A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types

接近单细胞分辨率的空间长读长测序方法揭示了不同皮层层级和细胞类型中剪接和多聚腺苷酸化位点的发育调控

Next-generation sequencing for guiding matched targeted therapies in people with relapsed or metastatic cancer

利用新一代测序技术指导复发或转移性癌症患者的靶向治疗

A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain

一项基于单细胞、长读长、亚型解析的FTD病例对照研究揭示了人脑中细胞类型特异性和广泛的剪接失调。

Development and characterisation of a fully recombinant competition ELISA for the diagnosis of foot-and-mouth disease virus infection

开发和表征用于诊断口蹄疫病毒感染的全重组竞争性ELISA

A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types.

接近单细胞分辨率的空间长读长方法揭示了不同皮层层和细胞类型中剪接和多聚腺苷酸化位点的发育调控

Spatial isoform sequencing at sub-micrometer single-cell resolution reveals novel patterns of spatial isoform variability in brain cell types.

亚微米单细胞分辨率的空间同工型测序揭示了脑细胞类型中空间同工型变异的新模式

Elevating levels of the endocannabinoid 2-arachidonoylglycerol blunts opioid reward but not analgesia

提高内源性大麻素 2-花生四烯酸甘油酯的水平会减弱阿片类药物的奖赏效应，但不会减弱其镇痛作用。

Inducing expression of ICOS-L by oncolytic adenovirus to enhance tumor-specific bi-specific antibody efficacy

溶瘤腺病毒诱导ICOS-L表达增强肿瘤特异性双特异性抗体疗效