For-Fan相关文献与解析，生知库 | 链接生命科学的每一步

Haifeng Fu #,Chunxiao Chen #,Yunying Huang #,Weiyu Zhang #,Shilong Li,For-Fan Chan,Ling Xu,Degong Ruan,Xiangyu Ouyang,Liyang Ma,Zhen Feng,Qingqing Zhang,Chunyan Wang,Dai Heng,Kexin Yao,Asif Javed,Chun-Ming Wong,Yin Lau Lee,William Shu Biu Yeung,Baofa Sun,Pentao Liu

Human

细胞生物学

发育与干细胞

Genome-wide CRISPR Screening Identifies NFÎºB and c-MET as Druggable Targets to Sensitize Lenvatinib Treatment in Hepatocellular Carcinoma.

全基因组 CRISPR 筛选发现 NFβ 和 c-MET 是可药物靶点，可增强 Lenvatinib 对肝细胞癌的治疗效果

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.4

doi:10.1016/j.jcmgh.2025.101502

Wan Ting-Chi Rebecca, Wei Lai, Cheng Lai-Hung, Chin Wai-Ching, Shen Jialing, Chan For-Fan, Kuang Zhijian, Wang Cun, Wong Carmen Chak-Lui, Wong Chun-Ming

细胞生物学

发表日期：2025

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N6-Methyladenosine modification activates the serine synthesis pathway to mediate therapeutic resistance in liver cancer.

N6-甲基腺苷修饰激活丝氨酸合成途径，从而介导肝癌的治疗耐药性

期刊:Molecular Therapy

影响因子:12

doi:10.1016/j.ymthe.2024.10.025

Chan For-Fan, Kwan Kenneth Kin-Leung, Seoung Do-Hyun, Chin Don Wai-Ching, Ng Irene Oi-Lin, Wong Carmen Chak-Lui, Wong Chun-Ming

ZEB1 Fuels Serine Metabolism to Promote HCC Metastasis

ZEB1促进丝氨酸代谢，从而促进肝细胞癌转移

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.4

doi:10.1016/j.jcmgh.2023.07.002

Chan, For-Fan; Wong, Chun-Ming

Targeting the Metabolic Vulnerability of ARID1A-Deficient Hepatocellular Carcinoma

针对ARID1A缺陷型肝细胞癌的代谢脆弱性进行治疗

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.4

doi:10.1016/j.jcmgh.2022.03.010

Chan, For-Fan; Wong, Chun-Ming

Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma

通过抑制硫氧还蛋白还原酶1诱导氧化应激是治疗肝细胞癌的有效方法

期刊:Hepatology

影响因子:15.8

doi:10.1002/hep.30467

Lee, Derek; Xu, Iris Ming-Jing; Chiu, David Kung-Chun; Leibold, Josef; Tse, Aki Pui-Wah; Bao, Macus Hao-Ran; Yuen, Vincent Wai-Hin; Chan, Cerise Yuen-Ki; Lai, Robin Kit-Ho; Chin, Don Wai-Ching; Chan, Daniel For-Fan; Cheung, Tan-To; Chok, Siu-Ho; Wong, Chun-Ming; Lowe, Scott W; Ng, Irene Oi-Lin; Wong, Carmen Chak-Lui

METTL3 safeguards cell identity and epigenome of human trophoblast stem cells

METTL3 保护人类滋养层干细胞的细胞特性和表观基因组

Genome-wide CRISPR Screening Identifies NFÎºB and c-MET as Druggable Targets to Sensitize Lenvatinib Treatment in Hepatocellular Carcinoma.

全基因组 CRISPR 筛选发现 NFβ 和 c-MET 是可药物靶点，可增强 Lenvatinib 对肝细胞癌的治疗效果

N6-Methyladenosine modification activates the serine synthesis pathway to mediate therapeutic resistance in liver cancer.

N6-甲基腺苷修饰激活丝氨酸合成途径，从而介导肝癌的治疗耐药性

ZEB1 Fuels Serine Metabolism to Promote HCC Metastasis

ZEB1促进丝氨酸代谢，从而促进肝细胞癌转移

Targeting the Metabolic Vulnerability of ARID1A-Deficient Hepatocellular Carcinoma

针对ARID1A缺陷型肝细胞癌的代谢脆弱性进行治疗

Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma

通过抑制硫氧还蛋白还原酶1诱导氧化应激是治疗肝细胞癌的有效方法