日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses

IFITM3 通过限制 Nogo-B 介导的 TLR 反应来限制病毒诱导的炎症细胞因子的产生

M Clement #, J L Forbester #, M Marsden, P Sabberwal, M S Sommerville, D Wellington, S Dimonte, S Clare, K Harcourt, Z Yin, L Nobre, R Antrobus, B Jin, M Chen, S Makvandi-Nejad, J A Lindborg, S M Strittmatter, M P Weekes, R J Stanton, T Dong, I R Humphreys

Genetic influences on viral-induced cytokine responses in the lung

遗传因素对肺部病毒诱导细胞因子反应的影响

Forbester, Jessica L; Humphreys, Ian R

IFITM3-specific antibody reveals IFN preferences and slow IFN induction of the antiviral factor IFITM3 in humans

IFITM3特异性抗体揭示了人类抗病毒因子IFITM3的IFN偏好性和IFN诱导缓慢性。

Wellington, Dannielle; Yin, Zixi; Abdel-Haq, Adi; Zhang, Liwei; Forbester, Jessica; Kite, Kerry; Rajapaksa, Ushani; Laurenson-Schafer, Henry; Makvandi-Nejad, Shokouh; Jin, Boquan; Bowes, Emma; Manoharan, Krishnageetha; Maldonado-Perez, David; Verrill, Clare; Humphreys, Ian R; Dong, Tao

Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2

巨噬细胞中 IL-10 信号的丧失限制了前列腺素 E2 驱动的细菌杀灭作用

Subhankar Mukhopadhyay, Eva Heinz, Immacolata Porreca, Kaur Alasoo, Amy Yeung, Huei-Ting Yang, Tobias Schwerd, Jessica L Forbester, Christine Hale, Chukwuma A Agu, Yoon Ha Choi, Julia Rodrigues, Melania Capitani, Luke Jostins-Dean, David C Thomas, Simon Travis, Daniel Gaffney, William C Skarnes, Nic

IRF5 Promotes Influenza Virus-Induced Inflammatory Responses in Human Induced Pluripotent Stem Cell-Derived Myeloid Cells and Murine Models

IRF5 促进人类诱导性多能干细胞衍生的髓系细胞和小鼠模型中流感病毒诱发的炎症反应

Jessica L Forbester, Mathew Clement, Dannielle Wellington, Amy Yeung, Sandra Dimonte, Morgan Marsden, Lucy Chapman, Eve L Coomber, Charlotte Tolley, Emily Lees, Christine Hale, Simon Clare, Irina Udalova, Tao Dong, Gordon Dougan, Ian R Humphreys

DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development

DNA甲基化决定了人类肠道上皮类器官的区域特性,并在发育过程中发生动态变化。

Kraiczy, Judith; Nayak, Komal M; Howell, Kate J; Ross, Alexander; Forbester, Jessica; Salvestrini, Camilla; Mustata, Roxana; Perkins, Sally; Andersson-Rolf, Amanda; Leenen, Esther; Liebert, Anke; Vallier, Ludovic; Rosenstiel, Philip C; Stegle, Oliver; Dougan, Gordon; Heuschkel, Robert; Koo, Bon-Kyoung; Zilbauer, Matthias

Genome-Wide Epigenetic and Transcriptomic Characterization of Human-Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids

人诱导多能干细胞来源的肠上皮类器官的全基因组表观遗传学和转录组学特征分析

Kraiczy, Judith; Ross, Alexander D B; Forbester, Jessica L; Dougan, Gordon; Vallier, Ludovic; Zilbauer, Matthias

An iPSC-Derived Myeloid Lineage Model of Herpes Virus Latency and Reactivation

疱疹病毒潜伏和再激活的iPSC衍生髓系模型

Poole, Emma; Huang, Christopher J Z; Forbester, Jessica; Shnayder, Miri; Nachshon, Aharon; Kweider, Baraa; Basaj, Anna; Smith, Daniel; Jackson, Sarah Elizabeth; Liu, Bin; Shih, Joy; Kiskin, Fedir N; Roche, K; Murphy, E; Wills, Mark R; Morrell, Nicholas W; Dougan, Gordon; Stern-Ginossar, Noam; Rana, Amer A; Sinclair, John

Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells

白细胞介素-22促进吞噬溶酶体融合,从而诱导人上皮细胞对鼠伤寒沙门氏菌的保护作用

Forbester, Jessica L; Lees, Emily A; Goulding, David; Forrest, Sally; Yeung, Amy; Speak, Anneliese; Clare, Simon; Coomber, Eve L; Mukhopadhyay, Subhankar; Kraiczy, Judith; Schreiber, Fernanda; Lawley, Trevor D; Hancock, Robert E W; Uhlig, Holm H; Zilbauer, Matthias; Powrie, Fiona; Dougan, Gordon

Interferon lambda is required for interferon gamma-expressing NK cell responses but does not afford antiviral protection during acute and persistent murine cytomegalovirus infection

干扰素λ是表达干扰素γ的NK细胞反应所必需的,但在急性或持续性小鼠巨细胞病毒感染期间不能提供抗病毒保护。

Gimeno Brias, Silvia; Marsden, Morgan; Forbester, Jessica; Clement, Mathew; Brandt, Cordelia; Harcourt, Katherine; Kane, Leanne; Chapman, Lucy; Clare, Simon; Humphreys, Ian R