Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides related to the anti-tumour drug temozolomide, with appended silicon, benzyl and heteromethyl groups at the 3-position

合成了与抗肿瘤药物替莫唑胺相关的咪唑并[5,1-d]-1,2,3,5-四嗪-8-甲酰胺类化合物，并在其3位引入了硅基、苄基和杂甲基，研究了这些化合物的生长抑制活性。