日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic and pharmacological inactivation of peptidoglycan remodeling increases antibiotic susceptibility of vancomycin-resistant Enterococcus faecium

通过基因和药理学手段抑制肽聚糖重塑可提高耐万古霉素粪肠球菌对抗生素的敏感性。

Fam, Kyong T; Chodisetti, Pavan Kumar; Wang, Zifei; Homer, Joshua A; Smedley, Christopher J; Kitamura, Seiya; Silva, Benjamin; Xiong, Yijun; Hansel-Harris, Althea; Holcomb, Matthew; Babarinde, Simeon; Turner, Adrianna M; Van Tyne, Daria; Wilson, Ian A; Forli, Stefano; Cravatt, Benjamin F; Park, Donghyun; Wolan, Dennis W; Moses, John E; Hang, Howard C

Replay and representation dynamics in the hippocampus of freely flying bats

自由飞行蝙蝠海马体中的重放和表征动态

Forli, Angelo; Fan, Wudi; Qi, Kevin K; Yartsev, Michael M

Structure-guided discovery of Otopetrin 1 inhibitors reveals druggable binding sites at the intrasubunit interface

基于结构的Otopetrin 1抑制剂发现揭示了亚基内界面处的可成药结合位点。

Batuujin Burendei #,Joshua P Kaplan #,Gerardo M Orellana,Emily R Liman,Stefano Forli,Andrew B Ward

Design principles of the common Gly-X6-Gly membrane protein building block

常见Gly-X6-Gly膜蛋白构建单元的设计原则

Golden, Kiana; Avarvarei, Catalina; Anderson, Charlie T; Holcomb, Matthew; Tang, Weiyi; Dai, Xiaoping; Zhang, Minghao; Mailie, Colleen A; Sanchez, Brittany B; Chen, Jason S; Forli, Stefano; Mravic, Marco

Sulfoxide-diazirine (SODA) as a Cleavable Photoaffinity Group To Enable the Identification of Photolabeled Modification Sites via LC-MS(3)

亚砜-重氮丙烯(SODA)作为可裂解的光亲和基团,可通过LC-MS(3)鉴定光标记修饰位点

Chen, Suyuan; Sanner, Michel F; Gracias Leone, Denise-Liu; Loroch, Stefan; Forli, Stefano; Verhelst, Steven H L

Structure-based rational design of covalent probes

基于结构的共价探针合理设计

Holcomb, Matthew; Llanos, Manuel; Hansel-Harris, Althea; Forli, Stefano

A quantitative analysis of ligand binding at the protein-lipid bilayer interface

对蛋白质-脂质双层界面配体结合的定量分析

Barkdull, Allison Pearl; Holcomb, Matthew; Forli, Stefano

Docking guidance with experimental ligand structural density improves docking pose prediction and virtual screening performance

利用实验配体结构密度进行对接指导可以提高对接姿态预测和虚拟筛选性能。

Hansel-Harris, Althea T; Tillack, Andreas F; Santos-Martins, Diogo; Holcomb, Matthew; Forli, Stefano

CIAA: Integrated Proteomics and Structural Modeling for Understanding Cysteine Reactivity with Iodoacetamide Alkyne

CIAA:整合蛋白质组学和结构建模以了解半胱氨酸与碘乙酰胺炔烃的反应性

Boatner, Lisa M; Eberhardt, Jerome; Shikwana, Flowreen; Holcomb, Matthew; Lee, Peiyuan; Houk, Kendall N; Forli, Stefano; Backus, Keriann M

IP6, PF74 affect HIV-1 capsid stability through modulation of hexamer-hexamer tilt angle preference

IP6和PF74通过调节六聚体-六聚体倾斜角偏好性影响HIV-1衣壳的稳定性。

Garza, Chris M; Holcomb, Matthew; Santos-Martins, Diogo; Torbett, Bruce E; Forli, Stefano