A human-ACE2 knock-in mouse model for SARS-CoV-2 infection recapitulates respiratory disorders but avoids neurological disease associated with the transgenic K18-hACE2 model.
用于 SARS-CoV-2 感染的人类 ACE2 敲入小鼠模型重现了呼吸系统疾病，但避免了与转基因 K18-hACE2 模型相关的神经系统疾病
期刊:mBio
影响因子:4.7
doi:10.1128/mbio.00720-25
Pons-GrÃfols Anna, Tarrés-Freixas Ferran, Pérez Mònica, Riveira-Muñoz Eva, Raïch-Regué Dà lia, Perez-Zsolt Daniel, Muñoz-Basagoiti Jordana, Tondelli Barbara, Pradenas Edwards, Izquierdo-Useros Nuria, Capdevila Sara, Vergara-Alert Júlia, Urrea Victor, Carrillo Jorge, Ballana Ester, Forrow Stephen, Clotet Bonaventura, Segalés Joaquim, Trinité Benjamin, Blanco JuliÃ
