日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates

非人灵长类动物脑脊液中AAV9载体递送的动力学和基于磁共振的监测

Ohno, Kousaku; Samaranch, Lluis; Hadaczek, Piotr; Bringas, John R; Allen, Philip C; Sudhakar, Vivek; Stockinger, Diane E; Snieckus, Christopher; Campagna, Michael V; San Sebastian, Waldy; Naidoo, Jerusha; Chen, Haifeng; Forsayeth, John; Salegio, Ernesto A; Hwa, Granger G C; Bankiewicz, Krystof S

Ganglioside Metabolism and Parkinson's Disease

神经节苷脂代谢与帕金森病

Forsayeth, John; Hadaczek, Piotr

Behavioral assessment of neuropathic pain, fatigue, and anxiety in experimental autoimmune encephalomyelitis (EAE) and attenuation by interleukin-10 gene therapy

实验性自身免疫性脑脊髓炎 (EAE) 中神经性疼痛、疲劳和焦虑的行为评估及其通过白细胞介素-10 基因疗法的缓解作用

Grace, Peter M; Loram, Lisa C; Christianson, John P; Strand, Keith A; Flyer-Adams, Johanna G; Penzkover, Kathryn R; Forsayeth, John R; van Dam, Anne-Marie; Mahoney, Melissa J; Maier, Steven F; Chavez, Raymond A; Watkins, Linda R

Depletion of AADC activity in caudate nucleus and putamen of Parkinson's disease patients; implications for ongoing AAV2-AADC gene therapy trial

帕金森病患者尾状核和壳核中AADC活性降低;对正在进行的AAV2-AADC基因治疗试验的影响

Ciesielska, Agnieszka; Samaranch, Lluis; San Sebastian, Waldy; Dickson, Dennis W; Goldman, Samuel; Forsayeth, John; Bankiewicz, Krystof S

Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease

非人灵长类动物大脑中广泛的AAV1和AAV2介导的转基因表达:对亨廷顿病的启示

Hadaczek, Piotr; Stanek, Lisa; Ciesielska, Agnieszka; Sudhakar, Vivek; Samaranch, Lluis; Pivirotto, Philip; Bringas, John; O'Riordan, Catherine; Mastis, Bryan; San Sebastian, Waldy; Forsayeth, John; Cheng, Seng H; Bankiewicz, Krystof S; Shihabuddin, Lamya S

Cerebellomedullary Cistern Delivery for AAV-Based Gene Therapy: A Technical Note for Nonhuman Primates

基于腺相关病毒(AAV)的基因治疗的小脑延髓池递送:非人灵长类动物技术说明

Samaranch, Lluis; Bringas, John; Pivirotto, Philip; Sebastian, Waldy San; Forsayeth, John; Bankiewicz, Krystof

AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction.

在非人灵长类动物中枢神经系统中,AAV9 介导的非自身蛋白表达会引发由抗原呈递细胞转导驱动的广泛神经炎症

Samaranch Lluis, Sebastian Waldy San, Kells Adrian P, Salegio Ernesto A, Heller Gregory, Bringas John R, Pivirotto Philip, DeArmond Stephen, Forsayeth John, Bankiewicz Krystof S

Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy

纳米颗粒在啮齿动物和非人灵长类动物大脑皮层的分布:对基因和药物治疗的启示

Salegio, Ernesto A; Streeter, Hillary; Dube, Nikhil; Hadaczek, Piotr; Samaranch, Lluis; Kells, Adrian P; San Sebastian, Waldy; Zhai, Yuying; Bringas, John; Xu, Ting; Forsayeth, John; Bankiewicz, Krystof S

Cerebral infusion of AAV9 vector-encoding non-self proteins can elicit cell-mediated immune responses.

将编码非自身蛋白的 AAV9 载体注入大脑可以引发细胞介导的免疫反应

Ciesielska Agnieszka, Hadaczek Piotr, Mittermeyer Gabriele, Zhou Shangzhen, Wright J Fraser, Bankiewicz Krystof S, Forsayeth John

Gene therapy for misfolding protein diseases of the central nervous system

基因疗法治疗中枢神经系统错误折叠蛋白疾病

San Sebastian, Waldy; Samaranch, Lluis; Kells, Adrian P; Forsayeth, John; Bankiewicz, Krystof S