日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Early plasma circulating tumor DNA (ctDNA) changes predict response to first-line pembrolizumab-based therapy in non-small cell lung cancer (NSCLC)

早期血浆循环肿瘤DNA(ctDNA)变化可预测非小细胞肺癌(NSCLC)患者对一线帕博利珠单抗治疗的反应

Ricciuti, Biagio; Jones, Greg; Severgnini, Mariano; Alessi, Joao V; Recondo, Gonzalo; Lawrence, Marissa; Forshew, Tim; Lydon, Christine; Nishino, Mizuki; Cheng, Michael; Awad, Mark

CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma

CTNNB1 突变在颅咽管瘤中呈克隆性

Apps, J R; Stache, C; Gonzalez-Meljem, J M; Gutteridge, A; Chalker, J; Jacques, T S; Forshew, T; Hölsken, A; Martinez-Barbera, J P

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells

儿童胶质母细胞瘤亚克隆群体与弥漫性内在性脑桥胶质瘤细胞之间的功能多样性和协同性

Mara Vinci, Anna Burford, Valeria Molinari, Ketty Kessler, Sergey Popov, Matthew Clarke, Kathryn R Taylor, Helen N Pemberton, Christopher J Lord, Alice Gutteridge, Tim Forshew, Diana Carvalho, Lynley V Marshall, Elizabeth Y Qin, Wendy J Ingram, Andrew S Moore, Ho-Keung Ng, Saoussen Trabelsi, Dorra H

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246

突变 p53 癌症通过外泌体 miR-1246 将巨噬细胞重编程为肿瘤支持巨噬细胞

Tomer Cooks, Ioannis S Pateras, Lisa M Jenkins, Keval M Patel, Ana I Robles, James Morris, Tim Forshew, Ettore Appella, Vassilis G Gorgoulis, Curtis C Harris

Comprehensive molecular characterisation of epilepsy-associated glioneuronal tumours

癫痫相关胶质神经元肿瘤的全面分子表征

Thomas J Stone, Angus Keeley, Alex Virasami, William Harkness, Martin Tisdall, Elisa Izquierdo Delgado, Alice Gutteridge, Tony Brooks, Mark Kristiansen, Jane Chalker, Lisa Wilkhu, William Mifsud, John Apps, Maria Thom, Mike Hubank, Tim Forshew, J Helen Cross, Darren Hargrave, Jonathan Ham, Thomas S

Dynamics of multiple resistance mechanisms in plasma DNA during EGFR-targeted therapies in non-small cell lung cancer

非小细胞肺癌EGFR靶向治疗期间血浆DNA中多种耐药机制的动态变化

Tsui, Dana Wai Yi; Murtaza, Muhammed; Wong, Alvin Seng Cheong; Rueda, Oscar M; Smith, Christopher G; Chandrananda, Dineika; Soo, Ross A; Lim, Hong Liang; Goh, Boon Cher; Caldas, Carlos; Forshew, Tim; Gale, Davina; Liu, Wei; Morris, James; Marass, Francesco; Eisen, Tim; Chin, Tan Min; Rosenfeld, Nitzan

Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling

对一种用于高灵敏度广谱分子谱分析的下一代测序液体活检检测方法进行分析验证

Plagnol, Vincent; Woodhouse, Samuel; Howarth, Karen; Lensing, Stefanie; Smith, Matt; Epstein, Michael; Madi, Mikidache; Smalley, Sarah; Leroy, Catherine; Hinton, Jonathan; de Kievit, Frank; Musgrave-Brown, Esther; Herd, Colin; Baker-Neblett, Katherine; Brennan, Will; Dimitrov, Peter; Campbell, Nathan; Morris, Clive; Rosenfeld, Nitzan; Clark, James; Gale, Davina; Platt, Jamie; Calaway, John; Jones, Greg; Forshew, Tim

Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA.

开发高灵敏度液体活检平台,以检测无细胞 DNA 中低等位基因频率的临床相关癌症突变

Gale Davina, Lawson Andrew R J, Howarth Karen, Madi Mikidache, Durham Bradley, Smalley Sarah, Calaway John, Blais Shannon, Jones Greg, Clark James, Dimitrov Peter, Pugh Michelle, Woodhouse Samuel, Epstein Michael, Fernandez-Gonzalez Ana, Whale Alexandra S, Huggett Jim F, Foy Carole A, Jones Gerwyn M, Raveh-Amit Hadas, Schmitt Karin, Devonshire Alison, Green Emma, Forshew Tim, Plagnol Vincent, Rosenfeld Nitzan

MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma

MAPK 通路控制胚胎垂体干细胞增殖和分化为乳头状颅咽管瘤的发病机制提供了见解

Scott Haston, Sara Pozzi, Gabriela Carreno, Saba Manshaei, Leonidas Panousopoulos, Jose Mario Gonzalez-Meljem, John R Apps, Alex Virasami, Selvam Thavaraj, Alice Gutteridge, Tim Forshew, Richard Marais, Sebastian Brandner, Thomas S Jacques, Cynthia L Andoniadou, Juan Pedro Martinez-Barbera

Digital PCR analysis of circulating tumor DNA: a biomarker for chondrosarcoma diagnosis, prognostication, and residual disease detection

循环肿瘤 DNA 的数字 PCR 分析:软骨肉瘤诊断、预后和残留疾病检测的生物标志物

Alice Gutteridge, Victoria M Rathbone, Rebecca Gibbons, Mark Bi, Nicholas Archard, Kate E J Davies, Jake Brown, Vincent Plagnol, Nischalan Pillay, Fernanda Amary, Paul O'Donnell, Manu Gupta, Roberto Tirabosco, Adrienne M Flanagan, Tim Forshew