日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Early plasma circulating tumor DNA (ctDNA) changes predict response to first-line pembrolizumab-based therapy in non-small cell lung cancer (NSCLC)

早期血浆循环肿瘤DNA(ctDNA)变化可预测非小细胞肺癌(NSCLC)患者对一线帕博利珠单抗治疗的反应

Ricciuti, Biagio; Jones, Greg; Severgnini, Mariano; Alessi, Joao V; Recondo, Gonzalo; Lawrence, Marissa; Forshew, Tim; Lydon, Christine; Nishino, Mizuki; Cheng, Michael; Awad, Mark

Dynamics of multiple resistance mechanisms in plasma DNA during EGFR-targeted therapies in non-small cell lung cancer

非小细胞肺癌EGFR靶向治疗期间血浆DNA中多种耐药机制的动态变化

Tsui, Dana Wai Yi; Murtaza, Muhammed; Wong, Alvin Seng Cheong; Rueda, Oscar M; Smith, Christopher G; Chandrananda, Dineika; Soo, Ross A; Lim, Hong Liang; Goh, Boon Cher; Caldas, Carlos; Forshew, Tim; Gale, Davina; Liu, Wei; Morris, James; Marass, Francesco; Eisen, Tim; Chin, Tan Min; Rosenfeld, Nitzan

Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling

对一种用于高灵敏度广谱分子谱分析的下一代测序液体活检检测方法进行分析验证

Plagnol, Vincent; Woodhouse, Samuel; Howarth, Karen; Lensing, Stefanie; Smith, Matt; Epstein, Michael; Madi, Mikidache; Smalley, Sarah; Leroy, Catherine; Hinton, Jonathan; de Kievit, Frank; Musgrave-Brown, Esther; Herd, Colin; Baker-Neblett, Katherine; Brennan, Will; Dimitrov, Peter; Campbell, Nathan; Morris, Clive; Rosenfeld, Nitzan; Clark, James; Gale, Davina; Platt, Jamie; Calaway, John; Jones, Greg; Forshew, Tim

Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA.

开发高灵敏度液体活检平台,以检测无细胞 DNA 中低等位基因频率的临床相关癌症突变

Gale Davina, Lawson Andrew R J, Howarth Karen, Madi Mikidache, Durham Bradley, Smalley Sarah, Calaway John, Blais Shannon, Jones Greg, Clark James, Dimitrov Peter, Pugh Michelle, Woodhouse Samuel, Epstein Michael, Fernandez-Gonzalez Ana, Whale Alexandra S, Huggett Jim F, Foy Carole A, Jones Gerwyn M, Raveh-Amit Hadas, Schmitt Karin, Devonshire Alison, Green Emma, Forshew Tim, Plagnol Vincent, Rosenfeld Nitzan

Molecular analysis of pediatric brain tumors identifies microRNAs in pilocytic astrocytomas that target the MAPK and NF-κB pathways

儿童脑肿瘤的分子分析发现,毛细胞型星形细胞瘤中存在靶向 MAPK 和 NF-κB 通路的 microRNA。

Jones, Tania A; Jeyapalan, Jennie N; Forshew, Tim; Tatevossian, Ruth G; Lawson, Andrew R J; Patel, Sheena N; Doctor, Gabriel T; Mumin, Muhammad A; Picker, Simon R; Phipps, Kim P; Michalski, Antony; Jacques, Thomas S; Sheer, Denise

Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis

食管癌发生过程中癌前病变阶段突变的顺序

Weaver, Jamie M J; Ross-Innes, Caryn S; Shannon, Nicholas; Lynch, Andy G; Forshew, Tim; Barbera, Mariagnese; Murtaza, Muhammed; Ong, Chin-Ann J; Lao-Sirieix, Pierre; Dunning, Mark J; Smith, Laura; Smith, Mike L; Anderson, Charlotte L; Carvalho, Benilton; O'Donovan, Maria; Underwood, Timothy J; May, Andrew P; Grehan, Nicola; Hardwick, Richard; Davies, Jim; Oloumi, Arusha; Aparicio, Sam; Caldas, Carlos; Eldridge, Matthew D; Edwards, Paul A W; Rosenfeld, Nitzan; Tavaré, Simon; Fitzgerald, Rebecca C

MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas

儿童低级别胶质瘤亚群中MYB上调和基因异常

Tatevossian, Ruth G; Tang, Bo; Dalton, James; Forshew, Tim; Lawson, Andrew R; Ma, Jing; Neale, Geoff; Shurtleff, Sheila A; Bailey, Simon; Gajjar, Amar; Baker, Suzanne J; Sheer, Denise; Ellison, David W