日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Intracellular uptake of agents that block the hERG channel can confound the assessment of QT interval prolongation and arrhythmic risk

细胞内摄取阻断hERG通道的药物可能会干扰QT间期延长和心律失常风险的评估。

期刊:Heart Rhythm
影响因子:5.7
doi:10.1016/j.hrthm.2021.08.028
Burashnikov, Alexander; Barajas-Martinez, Hector; Cox, Robert; Demitrack, Mark A; Fossler, Michael J; Kramer, Michael; Kleiman, Robert B; Kowey, Peter; Antzelevitch, Charles
ERG
细胞生物学
发表日期：2021
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Oliceridine is Associated with Reduced Risk of Vomiting and Need for Rescue Antiemetics Compared to Morphine: Exploratory Analysis from Two Phase 3 Randomized Placebo and Active Controlled Trials

与吗啡相比，奥利西啶可降低呕吐风险和使用补救性止吐药的需求：两项3期随机安慰剂和活性对照试验的探索性分析

期刊:Pain and Therapy
影响因子:3.3
doi:10.1007/s40122-020-00216-x
Beard, Timothy L; Michalsky, Cathy; Candiotti, Keith A; Rider, Paul; Wase, Linda; Habib, Ashraf S; Demitrack, Mark A; Fossler, Michael J; Viscusi, Eugene R
发表日期：2021
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Oliceridine Exhibits Improved Tolerability Compared to Morphine at Equianalgesic Conditions: Exploratory Analysis from Two Phase 3 Randomized Placebo and Active Controlled Trials

在等效镇痛条件下，奥利西啶与吗啡相比表现出更好的耐受性：来自两项3期随机安慰剂和活性对照试验的探索性分析

期刊:Pain and Therapy
影响因子:3.3
doi:10.1007/s40122-021-00299-0
Hammer, Gregory B; Khanna, Ashish K; Michalsky, Cathy; Wase, Linda; Demitrack, Mark A; Little, Roderick; Fossler, Michael J; Ayad, Sabry
发表日期：2021
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A Phase I, Randomized, Single‑Blind, Placebo‑Controlled, Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of Subcutaneous and Oral TRV250, a G Protein-Selective Delta Receptor Agonist, in Healthy Subjects

一项 I 期随机、单盲、安慰剂对照、单次递增剂量研究，旨在评估皮下和口服 TRV250（一种 G 蛋白选择性 Delta 受体激动剂）在健康受试者中的安全性、耐受性和药代动力学。

期刊:CNS Drugs
影响因子:7.4
doi:10.1007/s40263-020-00738-0
Fossler, Michael J; Schmith, Virginia; Greene, Stephen A; Lohmer, Lauren; Kramer, Michael S; Arscott, Kelly; James, Ian E; Demitrack, Mark A
信号转导
发表日期：2020
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Assessment of Demographic and Socio-Behavioral Factors on Adherence to HIV Pre-Exposure Prophylaxis Using a Markov Modeling Approach

利用马尔可夫模型方法评估人口统计学和社会行为因素对艾滋病毒暴露前预防依从性的影响

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2019.00785
Mallayasamy, Surulivelrajan; Chaturvedula, Ayyappa; Fossler, Michael J; Sale, Mark E; Hendrix, Craig W; Haberer, Jessica E
HIV
微生物学
发表日期：2019
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Tenofovir Plasma Concentration from Preexposure Prophylaxis at the Time of Potential HIV Exposure: a Population Pharmacokinetic Modeling and Simulation Study Involving Serodiscordant Couples in East Africa

东非血清不一致夫妇在潜在 HIV 暴露时接受暴露前预防治疗后替诺福韦血浆浓度：一项人群药代动力学建模和模拟研究

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00446-19
Mallayasamy, Surulivelrajan; Chaturvedula, Ayyappa; Fossler, Michael J; Sale, Mark; Goti, Vineet; Bumpus, Namandje N; Marzinke, Mark A; Hendrix, Craig W; Haberer, Jessica E
HIV
微生物学
发表日期：2019
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A Systematic Evaluation of Effect of Adherence Patterns on the Sample Size and Power of a Clinical Study

系统评价依从性模式对临床研究样本量和统计功效的影响

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.12361
Mallayasamy, Surulivelrajan; Chaturvedula, Ayyappa; Blaschke, Terrence; Fossler, Michael J
发表日期：2018
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A randomized, Phase IIb study investigating oliceridine (TRV130), a novel µ-receptor G-protein pathway selective (μ-GPS) modulator, for the management of moderate to severe acute pain following abdominoplasty

一项随机、IIb期研究，旨在探讨新型μ受体G蛋白通路选择性（μ-GPS）调节剂oliceridine（TRV130）在治疗腹部整形术后中度至重度急性疼痛方面的疗效。

期刊:Journal of Pain Research
影响因子:2.5
doi:10.2147/JPR.S137952
Singla, Neil; Minkowitz, Harold S; Soergel, David G; Burt, David A; Subach, Ruth Ann; Salamea, Monica Y; Fossler, Michael J; Skobieranda, Franck
信号转导
发表日期：2017
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Population Pharmacokinetics of Tenofovir in HIV-1-Uninfected Members of Serodiscordant Couples and Effect of Dose Reporting Methods

HIV-1 血清不一致伴侣中未感染 HIV-1 成员的替诺福韦群体药代动力学及剂量报告方法的影响

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00559-16
Lu, Yanhui; Goti, Vineet; Chaturvedula, Ayyappa; Haberer, Jessica E; Fossler, Michael J; Sale, Mark E; Bangsberg, David; Baeten, Jared M; Celum, Connie L; Hendrix, Craig W
HIV
炎症/感染
微生物学
发表日期：2016
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Evaluation of bioequivalence of five 0.1 mg dutasteride capsules compared to one 0.5 mg dutasteride capsule: a randomized study in healthy male volunteers

评估五粒0.1毫克度他雄胺胶囊与一粒0.5毫克度他雄胺胶囊的生物等效性：一项针对健康男性志愿者的随机研究

期刊:JOURNAL OF DRUG ASSESSMENT
影响因子:
doi:10.3109/21556660.2015.1067219
Fossler, Michael J; Collins, David A; Ino, Hiroko; Sarai, Nobuaki; Ravindranath, Ramiya; Bowen, Chester L; Burns, Olivia
发表日期：2015
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