日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A novel multiplex RNAi therapy simultaneously targets Hif1a and Hif2a to defy retinal degeneration in two models of AMD

一种新型多重RNAi疗法可同时靶向Hif1a和Hif2a，从而在两种AMD模型中阻止视网膜退化。

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2025.09.044
Ebner, Lynn J A; Imsand, Cornelia; Karademir, Duygu; Peters, Florian; Kiessling, Eva; Fottner, Antonia; Matter, Claudia; Fajardo, Diego S; Merolla, Luca; Wögenstein, Gabriele M; Tsioti, Ioanna; Govers, Larissa P; Blaser, Frank; Meneau, Isabelle; Boye, Sanford L; Boye, Shannon E; Grimm, Christian; Samardzija, Marijana
AMD
发表日期：2026
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RNA interference to reduce Egr1 expression in rods delays retinal degeneration in a model of retinitis pigmentosa

在视网膜色素变性模型中，通过RNA干扰降低视杆细胞中Egr1的表达可延缓视网膜色素变性的发生。

期刊:
影响因子:1.4
doi:
Merolla, Luca; Fottner, Antonia; Imsand, Cornelia; Matter, Claudia; Rowlan, Jessica; Neitz, Maureen; Govers, Larissa P; Samardzija, Marijana; Grimm, Christian
细胞生物学
发表日期：2026
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Combined [(18)F]Fluorodeoxyglucose PET and [(123)I]Iodometomidate-SPECT for diagnostic evaluation of indeterminate adrenal neoplasias-the cross-sectional diagnostic test accuracy study FAMIAN

联合应用[(18)F]氟代脱氧葡萄糖PET和[(123)I]碘甲咪酯-SPECT诊断评估肾上腺未定肿瘤——横断面诊断试验准确性研究FAMIAN

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2025.105735
Hahner, Stefanie; Hartrampf, Philipp; Beuschlein, Felix; Miederer, Matthias; Miehle, Konstanze; Schlötelburg, Wiebke; Fuß, Carmina Teresa; Pfluger, Thomas; Fottner, Christian; Tönjes, Anke; Herrmann, Ken; Amthauer, Holger; Reincke, Martin; Schreckenberger, Mathias; Sabri, Osama; Werner, Johanna; Reuter, Miriam; Kircher, Stefan; Arlt, Wiebke; Fassnacht, Martin; Konrad Buck, Andreas; Müller, Hans-Helge; Schirbel, Andreas
MIA
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2025
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HIF1 activity in photoreceptors drives type 3 neovascularization and retinal atrophy in a new mouse model of age-related macular degeneration

在一种新的年龄相关性黄斑变性小鼠模型中，感光细胞中的HIF1活性驱动3型新生血管形成和视网膜萎缩。

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-08028-7
Geiger, Fredy; Heigl, Thomas; Merolla, Luca; Yong, Marcus; Wögenstein, Gabriele M; Govers, Larissa P; Tsioti, Ioanna; Fottner, Antonia; Samardzija, Marijana; Grimm, Christian
细胞生物学
发表日期：2025
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One-pot dual protein labeling for simultaneous mechanical and fluorescent readouts in optical tweezers

用于光镊中同时进行机械和荧光读数的单步双蛋白标记

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.70098
Silbermann, Laura-Marie; Fottner, Maximilian; van der Meulen, Ronald; Migdad, Nora; Lang, Kathrin; Tych, Katarzyna
IF
发表日期：2025
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Imaging-derived biomarkers from (68)Ga-DOTATOC PET/CT scans to predict survival of patients with neuroendocrine tumors after PRRT with (177)Lu-DOTATATE

利用 (68)Ga-DOTATOC PET/CT 扫描的影像衍生生物标志物预测接受 (177)Lu-DOTATATE 肽受体放射性核素治疗 (PRRT) 的神经内分泌肿瘤患者的生存期。

期刊:Cancer Imaging
影响因子:3.5
doi:10.1186/s40644-025-00899-5
Raad, Stephan; Al-Fatlawi, Ali; Wise, C Louise; Fottner, Christian; Schadmand-Fischer, Simin; Schreckenberger, Mathias; Weber, Matthias M; Musholt, Thomas J; Schroeder, Michael; Miederer, Matthias
信号转导
肿瘤
肿瘤免疫
发表日期：2025
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Bridging the gap between models and reality: development of a research environment for an object-oriented hospital information system to integrate artificial intelligence and robotics into clinical practice

弥合模型与现实之间的差距：开发面向对象的医院信息系统研究环境，将人工智能和机器人技术融入临床实践

期刊:International Journal of Computer Assisted Radiology and Surgery
影响因子:2.3
doi:10.1007/s11548-025-03470-6
Rashid, Sidra; Bernhard, Lukas; Stabenow, Sonja; Spicker, Emily; Haid, Charlotte; König, Carl; Kramer, Hedi Louise; Pischinger, Sandro; Schade, Daniel; Fottner, Johannes; Wilhelm, Dirk; Berlet, Maximilian
发表日期：2025
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Clinical characteristics and treatment patterns of patients with gastroenteropancreatic neuroendocrine neoplasia in Germany receiving peptide receptor radionuclide therapy: A real-world data registry-based study

德国接受肽受体放射性核素治疗的胃肠胰神经内分泌肿瘤患者的临床特征和治疗模式：一项基于真实世界数据注册的研究

期刊:Medicine
影响因子:1.4
doi:10.1097/MD.0000000000041853
von Hessert-Vaudoncourt, Claus; Maasberg, Sebastian; Begum, Nehara; Rinke, Anja; Pöppel, Thorsten; Sipos, Bence; Grohe, Christian; Fottner, Christian; Stintzing, Sebastian; Grabowski, Patricia
信号转导
肿瘤
肿瘤免疫
发表日期：2025
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The functional landscape of the human ubiquitinome

人类泛素组的功能图谱

期刊:
影响因子:
doi:10.1101/2025.10.08.681129
van Gerwen, Julian; Fottner, Maximilian; Wang, Shengbo; Busby, Bede; Boswell, Ellen; Schnacke, Paul; Carrano, Andrea C; Bakowski, Malina A; Troemel, Emily R; Studer, Romain; Strumillo, Marta; Martin, Maria-Jesus; Harper, J Wade; Lang, Kathrin; Jones, Andrew R; Bennett, Eric J; Vizcaíno, Juan Antonio; Barrio-Hernandez, Inigo; Beltrao, Pedro
发表日期：2025
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Genetic Code Expansion Approaches to Decipher the Ubiquitin Code

利用遗传密码扩展方法破译泛素密码

期刊:Chemical Reviews
影响因子:55.8
doi:10.1021/acs.chemrev.4c00375
Wanka, Vera; Fottner, Maximilian; Cigler, Marko; Lang, Kathrin
发表日期：2024
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