日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MEK Inhibition Reduces Vascular Malformations and Gene Dysregulation in NRAS(Q61R) Human Endothelial Cells

MEK抑制剂可减少NRAS(Q61R)人内皮细胞中的血管畸形和基因失调

Alharbi, Sara; Wagner, Andrew; Merkle, Svatava; Pastura, Patricia; McDaniel, C Griffin; Fox, Dermot; Xu, Yan; Cras, Timothy D Le

Human Lymphatic Endothelial Cells Expressing NRAS(Q61R) Model Characteristics of Kaposiform Lymphangiomatosis

表达NRAS(Q61R)的人类淋巴管内皮细胞:卡波西样淋巴管瘤病的模型特征

Fox, Dermot A; McDaniel, C Griffin; Pastura, Patricia; Le Cras, Timothy D

Lyve1-Driven Nras(Q61R) Causes Edema, Enlarged Lymphatic Vessels, and Hepatic Vascular Defects in Embryonic Mice.

Lyve1 驱动的 Nras(Q61R) 导致胚胎小鼠出现水肿、淋巴管增大和肝血管缺陷。

McDaniel C Griffin, Fox Dermot, Pastura Patricia, Alharbi Sara, Huppert Stacey S, Cras Timothy D Le

NRAS(Q61R) mutation drives elevated angiopoietin-2 expression in human endothelial cells and a genetic mouse model.

NRAS(Q61R)突变驱动人类内皮细胞和基因小鼠模型中血管生成素-2表达升高

Pastura Patricia, McDaniel C Griffin, Alharbi Sara, Fox Dermot, Coleman Bethany, Malik Punam, Adams Denise M, Le Cras Timothy D