日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genomic Therapy Matching in Rare and Refractory Cancers

罕见和难治性癌症的基因组治疗匹配

Lin, Frank P; Thavaneswaran, Subotheni; Grady, John P; Napier, Christine E; Kansara, Maya; Sebastian, Lucille; Kee, Damien; Desai, Jayesh; Zaheed, Milita; Chinchen, Sarah; Oakes, Samantha R; Blackburn, James; Scott, Hamish S; Glover, Anthony; Fox, Stephen B; Goldstein, David; Leo, Paul; Amanuel, Benhur; Mersiades, Antony; Millward, Michael; Brown, Michael P; Charakidis, Michail; Pokorny, Adrian M J; Craft, Paul; Espinoza, David; Grimison, Peter; Harrup, Rosemary; Joshua, Anthony M; O'Byrne, Ken; Lee, Chee Khoon; Cowley, Mark J; Ballinger, Mandy L; Simes, John; Thomas, David M

Breast cancers arising in high mammographic density tissue harbor tumor-promoting immune profiles.

发生于乳腺X线密度较高组织的乳腺癌具有促进肿瘤生长的免疫特征。

Cheasley Dane, Ruppert Meagan, Devereux Lisa, Jayawardana Madawa W, Zhao Qihong, Nickson Carolyn, Pereira Melrine, Byrne David J, Fox Stephen B, Campbell Ian G, Britt Kara L

Phylogenetic analysis of paired breast carcinomas identifies genetic events associated with clonal recurrence and invasive progression

对配对乳腺癌的系统发育分析可识别与克隆复发和侵袭性进展相关的遗传事件。

Kader, Tanjina; Zethoven, Maia; Mahale, Sakshi; Saunders, Hugo; Tjoeka, Lauren; Lehmann, Rebecca; Jayawardana, Madawa W; Pang, Jia-Min; Lesche, Dorothea; Rajan, Neeha; Semple, Timothy; Lee, Jue Er Amanda; Lupat, Richard; Byrne, David J; Hughes, Siobhan; Nguyen, Hoa; Lai, Siqi; Pechlivanis, Maree; Craig, Olivia; Devereux, Lisa; House, Eloise; Jayasinghe, Sureshni I; Kaufmann, Tom L; Schwarz, Roland F; Green, Andrew R; Miligy, Islam M; Cummings, Margaret; Lakhani, Sunil; Campbell, Ian G; Rakha, Emad; Fox, Stephen B; Mann, G Bruce; Gorringe, Kylie L

Molecular pathology of phyllodes tumours of the breast-much more than MED12

乳腺叶状肿瘤的分子病理学——远不止MED12

Pang, Jia-Min B; Gorringe, Kylie L; Tan, Puay Hoon; Fox, Stephen B

Pathologist-initiated whole genome and transcriptome sequencing demonstrates diagnostic utility in resolving difficult-to-diagnose tumors

病理学家发起的全基因组和转录组测序在解决疑难肿瘤诊断方面展现出诊断价值

Vissers, Joseph H A; Mitchell, Catherine; Prall, Owen W J; Lo, Wing-Yee; Kanwal, Sehrish; Luen, Stephen J; Watts, Stephen C; Angel, Christopher M; Khoo, Christine; Pang, Jia-Min B; Murray, William K; Snell, Cameron; Christie, Michael; Rebello, Richard J; Tothill, Richard W; Pham, Kym; Hofmann, Oliver; Fox, Stephen B; Grimmond, Sean M

Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine.

通过对 CaaX 盒半胱氨酸进行直接共价攻击,阻断 KRAS4b 的 C 端加工

Maciag Anna E, Yang Yue, Sharma Alok K, Turner David M, DeHart Caroline J, Abdelkarim Hazem, Fan Lixin, Smith Brian P, Kumari Vandana, Dyba Marcin, Rigby Megan, Castillo Badillo Jean A, Adams Lauren, Fornelli Luca, Fox Stephen, Brafman Alla, Turbyville Thomas, Gillette William, Messing Simon, Agamasu Constance, Wolfe Andrew L, Gysin Stephan, Chan Albert H, Simanshu Dhirendra K, Esposito Dominic, Chertov Oleg, Stephen Andrew G, Arkin Michelle, Renslo Adam, Kelleher Neil L, Gaponenko Vadim, Lightstone Felice C, Nissley Dwight V, McCormick Frank

Using artificial intelligence (AI) to model clinical variant reporting for next generation sequencing (NGS) oncology assays

利用人工智能(AI)对下一代测序(NGS)肿瘤检测的临床变异报告进行建模

Doig, Kenneth D; Perera, Rashindrie; Kankanige, Yamuna; Fellowes, Andrew; Li, Jason; Lupat, Richard; Thompson, Ella R; Blombery, Piers; Fox, Stephen B

Functional Characterization and a Real-World Clinical Laboratory Pilot of the Foundation for the National Institutes of Health Circulating Tumor DNA Quality Control Materials

美国国立卫生研究院基金会循环肿瘤DNA质量控制材料的功能表征和真实世界临床实验室试点项目

Paweletz, Cloud P; Forbes, Thomas D; Yee, Laura; Heavey, Grace; He, Hua-Jun; He, Zhiyong; Connors, Dana; Stetson, Daniel; Keating, Susan; Cole, Kenneth D; Chen, Li; Pauly, Rini; Bao, Hua; Wu, Xue; Pestano, Gary A; Weaver, Amanda L; Kohli, Manish; Hellwig, Sabine; Corner, Adam S; Prantner, Andrew M; Wong, Stephen Q; Fox, Stephen B; Hewitt, Chelsee A; Arnolda, Rainier; Jones, Greg R; Craft, Jonathan; McConechy, Melissa; Qahtani, Mawath A; Klemm, Florian; Mohammad, Fuad; Sigman, Caroline; Liu, Liang-Chun; Gan, Qiang; Konigshofer, Yves; Garlick, Russell; Chin, Ephrem; Kelloff, Gary; Williams, P Mickey; McCormack, Robert; Karlovich, Chris

5hmC enhances PARP trapping and restores PARP inhibitor sensitivity in chemoresistant BRCA1/2-deficient cells.

5hmC 增强 PARP 捕获并恢复对化疗耐药的 BRCA1/2 缺陷细胞的 PARP 抑制剂敏感性

Kharat Suhas S, Mishra Arun P, Sengodan Satheesh K, Dierman Dillon, Fox Stephen D, Chazin Walter J, Sharan Shyam K

Preliminary characterisation of the spatial immune and vascular environment in triple negative basal breast carcinomas using multiplex fluorescent immunohistochemistry

利用多重荧光免疫组织化学技术对三阴性基底型乳腺癌的空间免疫和血管环境进行初步表征

Takano, Elena A; Jana, Metta K; Lara Gonzalez, Luis E; Pang, Jia-Min B; Salgado, Roberto; Loi, Sherene; Fox, Stephen B