Fox Todd相关文献与解析，生知库 | 链接生命科学的每一步

肿瘤免疫

炎症

T细胞

线粒体

凋亡

转录调控

巨噬细胞

自噬

传染病

氧化应激

肠道菌群

磷酸化

血管生成

囊泡

3D/类器官

单细胞

中性粒细胞

外泌体

DNA甲基化

miRNA

药物研究

铁死亡

细胞衰老

乙酰化

缺氧低氧

泛素化

树突状细胞

炎性小体

组蛋白修饰

肿瘤微环境

lncRNA

代谢重编程

焦亡

m6A/m5C/m7G

内质网应激

空间多组学

细胞基因治疗

治疗耐药

相分离

Treg

上皮间质转化

免疫代谢

染色质重塑

脂质过氧化

蛋白质稳态

脂代谢

细胞极性

铁代谢

氨基酸代谢

碱基编辑

cGAS-STING

肠脑轴

蛋白降解

乳酸化

翻译调控

circRNA

piRNA

肿瘤异质性

NK 细胞

氧化脂质

MDSC

NETosis

低氧缺氧

溶酶体功能

琥珀酰化

细胞干性

CAR-NK

冷应激

RNA 编辑

Tfh

巴豆酰化

器官芯片

表观遗传记忆

铜死亡

器官纤维化

线粒体未折叠蛋白反应

空间代谢组

程序性坏死

自噬流

MAIT 细胞

肠肝轴

丙酰化

日期影响因子

Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia

酸性神经酰胺酶抑制剂可增强维奈托克耐药急性髓系白血病中 BCL-2 的靶向作用

doi:10.1016/j.bneo.2026.100196

Ung, Johnson; Tan, Su-Fern; Shaw, Jeremy J P; Taori, Maansi; Deddens, Tess M; Venancio, Giovana; Montgomery, McLane M; Hagen, James T; Aruleba, Raphael T; Golla, Upendar R; Sharma, Arati; Paudel, B Bishal; Lee, Irene; Ramamoorthy, Bhavishya; Janes, Kevin A; Garrett-Bakelman, Francine; Cabot, Myles C; Fisher-Wellman, Kelsey H; Fox, Todd E; Claxton, David F; Chalfant, Charles E; Feith, David J; Loughran, Thomas P Jr

发表日期：2026

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Nanoromidepsin, a polymer nanoparticle of the HDAC inhibitor, improves safety and efficacy in models of T-cell lymphoma

纳米罗米地辛（一种HDAC抑制剂的聚合物纳米颗粒）可提高T细胞淋巴瘤模型中的安全性和有效性。

影响因子:23.1

doi:10.1182/blood.2024027997

Pal, Ipsita; Illendula, Anuradha; Joyner, Andrea; Manavalan, John Sanil; Deddens, Tess M; Sabzevari, Ariana; Damera, Deepthi P; Zuberi, Samir; Marchi, Enrica; Fox, Todd E; Dunlap-Brown, Marya E; Jayappa, Kallesh D; Khalife, Jihane; Craig, Jeffrey W; Loughran, Thomas P Jr; Feith, David J; O'Connor, Owen A

免疫/内分泌

细胞生物学

发表日期：2025

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Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia via a cytotoxic integrated stress response

酸性神经酰胺酶抑制剂通过细胞毒性整合应激反应增强维奈托克耐药急性髓系白血病中BCL-2的靶向作用

doi:10.1101/2025.06.06.657881

Ung, Johnson; Tan, Su-Fern; Shaw, Jeremy J P; Taori, Maansi; Deddens, Tess M; Venancio, Giovana da Costa; Montgomery, McLane M; Hagen, James T; Aruleba, Raphael T; Golla, Upendar R; Sharma, Arati; Paudel, B Bishal; Lee, Irene Sung-Ah; Ramamoorthy, Bhavishya; Janes, Kevin A; Garrett-Bakelman, Francine; Cabot, Myles C; Fisher-Wellman, Kelsey H; Fox, Todd E; Claxton, David F; Chalfant, Charles E; Feith, David J; Loughran, Thomas P

细胞生物学

发表日期：2025

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Heparin-enriched plasma proteome is significantly altered in Alzheimer's disease

富含肝素的血浆蛋白质组在阿尔茨海默病中发生显著改变

期刊:Molecular Neurodegeneration

影响因子:14.9

doi:10.1186/s13024-024-00757-1

Qi Guo #, Lingyan Ping #, Eric B Dammer, Duc M Duong, Luming Yin, Kaiming Xu, Anantharaman Shantaraman, Edward J Fox, Todd E Golde, Erik C B Johnson, Blaine R Roberts, James J Lah, Allan I Levey, Nicholas T Seyfried2

阿尔茨海默症

发表日期：2024

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Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes

急性髓系白血病根据鞘脂组学特征可分为 2 个临床相关的亚型。

期刊:Blood Advances

影响因子:7.1

doi:10.1182/bloodadvances.2023010535

Paudel, B Bishal; Tan, Su-Fern; Fox, Todd E; Ung, Johnson; Golla, Upendarrao; Shaw, Jeremy J P; Dunton, Wendy; Lee, Irene; Fares, Wisam A; Patel, Satyam; Sharma, Arati; Viny, Aaron D; Barth, Brian M; Tallman, Martin S; Cabot, Myles; Garrett-Bakelman, Francine E; Levine, Ross L; Kester, Mark; Feith, David J; Claxton, David; Janes, Kevin A; Loughran, Thomas P Jr

发表日期：2024

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A phase I study of the ceramide nanoliposome in patients with advanced solid tumors

一项针对晚期实体瘤患者的神经酰胺纳米脂质体的I期研究

期刊:Cancer Chemotherapy and Pharmacology

影响因子:2.3

doi:10.1007/s00280-023-04588-7

Ciner, Aaron; Gourdin, Theodore; Davidson, Jeff; Parette, Mylisa; Walker, Susan J; Fox, Todd E; Jiang, Yixing

发表日期：2024

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Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease

富含肝素的血浆蛋白质组在阿尔茨海默病中发生显著改变

doi:10.21203/rs.3.rs-3933136/v1

Qi Guo, Lingyan Ping, Eric B Dammer, Luming Yin, Kaiming Xu, Anantharaman Shantaraman, Edward J Fox, Todd E Golde, Erik C B Johnson, Blaine R Roberts, James J Lah, Allan I Levey, Nicholas T Seyfried

阿尔茨海默症

发表日期：2024

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Solid tumor treatment via augmentation of bioactive C6 ceramide levels with thermally ablative focused ultrasound

利用热消融聚焦超声提高生物活性C6神经酰胺水平治疗实体瘤

期刊:Drug Delivery and Translational Research

影响因子:5.5

doi:10.1007/s13346-023-01377-w

Thim, E Andrew; Fox, Todd; Deering, Tye; Vass, Luke R; Sheybani, Natasha D; Kester, Mark; Price, Richard J

发表日期：2023

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Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia

同时抑制神经酰胺水解和糖基化可协同破坏线粒体呼吸并诱导耐药性急性髓系白血病中的caspase驱动的细胞死亡。

影响因子:4.4

doi:10.3390/cancers15061883

Fisher-Wellman, Kelsey H; Kassai, Miki; Hagen, James T; Neufer, P Darrell; Kester, Mark; Loughran, Thomas P Jr; Chalfant, Charles E; Feith, David J; Tan, Su-Fern; Fox, Todd E; Ung, Johnson; Fabrias, Gemma; Abad, Jose' Luis; Sharma, Arati; Golla, Upendarrao; Claxton, David F; Shaw, Jeremy J P; Bhowmick, Debajit; Cabot, Myles C

细胞生物学

发表日期：2023

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Solid Tumor Treatment via Augmentation of Bioactive C6 Ceramide Levels with Thermally Ablative Focused Ultrasound

利用热消融聚焦超声提高生物活性C6神经酰胺水平治疗实体瘤

doi:10.1101/2023.03.23.532394

Thim, E Andrew; Fox, Todd; Deering, Tye; Vass, Luke R; Sheybani, Natasha D; Kester, Mark; Price, Richard J

发表日期：2023

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