日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.

Tlr7 驱动与年龄和阿尔茨海默病相关的脱髓鞘的性别差异

Lopez-Lee Chloe, Kodama Lay, Fan Li, Zhu Daphne, Zhu Jingjie, Wong Man Ying, Ye Pearly, Norman Kendra, Foxe Nessa R, Ijaz Laraib, Yu Fangmin, Chen Hao, Carling Gillian K, Torres Eileen R, Kim Rachel D, Dubal Dena B, Liddelow Shane A, Sinha Subhash C, Luo Wenjie, Gan Li

Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.

阿尔茨海默病相关风险等位基因在 tau 蛋白病模型中加剧小胶质细胞 cGAS 相关的衰老和神经退行性变

Carling Gillian K, Fan Li, Foxe Nessa R, Norman Kendra, Wong Man Ying, Zhu Daphne, Corona Carlo, Razzoli Agnese, Yu Fangmin, Yarahmady Allan, Ye Pearly, Chen Hao, Huang Yige, Amin Sadaf, Sereda Rebecca, Lopez-Lee Chloe, Zacharioudakis Emmanouil, Chen Xiaoying, Xu Jielin, Cheng Feixiong, Gavathiotis Evripidis, Cuervo Ana Maria, Holtzman David M, Mok Sue-Ann, Sinha Subhash C, Sidoli Simone, Ratan Rajiv R, Luo Wenjie, Gong Shiaoching, Gan Li

Sex Chromosomes and Gonads Shape the Sex-Biased Transcriptomic Landscape in Tlr7-Mediated Demyelination During Aging

性染色体和性腺塑造了衰老过程中Tlr7介导的脱髓鞘过程中性别偏向的转录组图谱

Lopez-Lee, Chloe; Kodama, Lay; Fan, Li; Wong, Man Ying; Foxe, Nessa R; Jiaz, Laraib; Yu, Fangmin; Ye, Pearly; Zhu, Jingjie; Norman, Kendra; Torres, Eileen Ruth; Kim, Rachel D; Mousa, Gergey Alzaem; Dubal, Dena; Liddelow, Shane; Luo, Wenjie; Gan, Li