日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting the activated microenvironment with endosialin (CD248)-directed CAR-T cells ablates perivascular cells to impair tumor growth and metastasis

利用靶向内皮唾液酸蛋白(CD248)的CAR-T细胞攻击活化的微环境,可清除血管周围细胞,从而抑制肿瘤生长和转移。

Sarah L Ash ,Rebecca Orha ,Holly Mole ,Meg Dinesh-Kumar ,Steven P Lee ,Frances K Turrell # ,Clare M Isacke #

Age-associated microenvironmental changes highlight the role of PDGF-C in ER+ breast cancer metastatic relapse

与年龄相关的微环境变化凸显了 PDGF-C 在 ER+ 乳腺癌转移性复发中的作用

Frances K Turrell, Rebecca Orha, Naomi J Guppy, Andrea Gillespie, Matthew Guelbert, Chris Starling, Syed Haider, Clare M Isacke

Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity

具有不同p53突变的肺癌肿瘤对p53靶向治疗的反应相似,但对他汀类药物的敏感性存在基因型特异性。

Frances K Turrell ,Emma M Kerr ,Meiling Gao ,Hannah Thorpe ,Gary J Doherty ,Jake Cridge ,David Shorthouse ,Alyson Speed ,Shamith Samarajiwa ,Benjamin A Hall ,Meryl Griffiths ,Carla P Martins

Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities

突变 Kras 拷贝数决定代谢重编程和治疗敏感性

Emma M Kerr, Edoardo Gaude, Frances K Turrell, Christian Frezza, Carla P Martins