Examining the chirality, conformation and selective kinase inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (CP-690,550)
检查 3-((3R,4R)-4-甲基-3-(甲基(7H-吡咯并[2,3-d]嘧啶-4-基)氨基)哌啶-1-基)-3-氧代丙腈 (CP-690,550) 的手性、构象和选择性激酶抑制
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm801142b
Jian-kang Jiang, Kamran Ghoreschi, Francesca Deflorian, Zhi Chen, Melissa Perreira, Marko Pesu, Jeremy Smith, Dac-Trung Nguyen, Eric H Liu, William Leister, Stefano Costanzi, John J O'Shea, Craig J Thomas
