Francesca Gado相关文献与解析，生知库 | 链接生命科学的每一步

A Proteomic Approach Identified TFEB as a Key Player in the Protective Action of Novel CB2R Bitopic Ligand FD22a against the Deleterious Effects Induced by β-Amyloid in Glial Cells

蛋白质组学方法确定 TFEB 是新型 CB2R 双位配体 FD22a 对抗 β-淀粉样蛋白在神经胶质细胞中引起的有害影响的保护作用中的关键因素

Beatrice Polini, Lorenzo Zallocco, Francesca Gado, Rebecca Ferrisi, Caterina Ricardi, Mariachiara Zuccarini, Vittoria Carnicelli, Clementina Manera, Maurizio Ronci, Antonio Lucacchini, Riccardo Zucchi, Laura Giusti, Grazia Chiellini

神经

New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2

对 2 型大麻素受体双位正构/变构配体的新见解

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms24032135

Rebecca Ferrisi, Beatrice Polini, Caterina Ricardi, Francesca Gado, Kawthar A Mohamed, Giovanna Baron, Salvatore Faiella, Giulio Poli, Simona Rapposelli, Giuseppe Saccomanni, Giancarlo Aldini, Grazia Chiellini, Robert B Laprairie, Clementina Manera, Gabriella Ortore

信号转导

发表日期：2023

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Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands

新型 CB2 受体配体的设计、合成和生物活性：从正构和变构调节剂到双立体/双位配体

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.2c00582

Francesca Gado, Rebecca Ferrisi, Beatrice Polini, Kawthar A Mohamed, Caterina Ricardi, Elena Lucarini, Sara Carpi, Federica Domenichini, Lesley A Stevenson, Simona Rapposelli, Giuseppe Saccomanni, Paola Nieri, Gabriella Ortore, Roger G Pertwee, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Grazia Ch

信号转导

发表日期：2022

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Achillea moschata Wulfen: From Ethnobotany to Phytochemistry, Morphology, and Biological Activity

蓍草：从民族植物学到植物化学、形态学和生物活性

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules27238318

Martina Bottoni, Giovanna Baron, Francesca Gado, Fabrizia Milani, Laura Santagostini, Lorenzo Colombo, Paola Sira Colombo, Elisabetta Caporali, Alberto Spada, Marco Biagi, Claudia Giuliani, Piero Bruschi, Giancarlo Aldini, Gelsomina Fico

发表日期：2022

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Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells

选择性大麻素 CB2 受体激动剂的合成及体外表征：针对神经母细胞瘤癌细胞的生物学评价

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules27093019

Francesca Gado, Rebecca Ferrisi, Sarah Di Somma, Fabiana Napolitano, Kawthar A Mohamed, Lesley A Stevenson, Simona Rapposelli, Giuseppe Saccomanni, Giuseppe Portella, Roger G Pertwee, Robert B Laprairie, Anna Maria Malfitano, Clementina Manera

Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R)

大麻素受体 2 型（CB2R）新型正构-变构配体的设计、合成及生物学评价

期刊:Frontiers in Chemistry

影响因子:3.8

doi:10.3389/fchem.2022.984069

Rebecca Ferrisi, Francesca Gado, Beatrice Polini, Caterina Ricardi, Kawthar A Mohamed, Lesley A Stevenson, Gabriella Ortore, Simona Rapposelli, Giuseppe Saccomanni, Roger G Pertwee, Robert B Laprairie, Clementina Manera, Grazia Chiellini

信号转导

发表日期：2022

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Liquid Chromatography-High-Resolution Mass Spectrometry (LC-HRMS) Profiling of Commercial Enocianina and Evaluation of Their Antioxidant and Anti-Inflammatory Activity

液相色谱-高分辨率质谱 (LC-HRMS) 对商用 Enocianina 进行分析并评估其抗氧化和抗炎活性

期刊:Antioxidants

影响因子:

doi:10.3390/antiox11061187

Larissa Della Vedova, Giulio Ferrario, Francesca Gado, Alessandra Altomare, Marina Carini, Paolo Morazzoni, Giancarlo Aldini, Giovanna Baron

免疫

发表日期：2022

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Anti-Inflammatory Activity of a CB2 Selective Cannabinoid Receptor Agonist: Signaling and Cytokines Release in Blood Mononuclear Cells

CB2 选择性大麻素受体激动剂的抗炎活性：血液单核细胞中的信号传导和细胞因子释放

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules27010064

Antonella Capozzi, Daniela Caissutti, Vincenzo Mattei, Francesca Gado, Stefano Martellucci, Agostina Longo, Serena Recalchi, Valeria Manganelli, Gloria Riitano, Tina Garofalo, Maurizio Sorice, Clementina Manera, Roberta Misasi

Positive Allosteric Modulation of CB1 and CB2 Cannabinoid Receptors Enhances the Neuroprotective Activity of a Dual CB1R/CB2R Orthosteric Agonist

CB1 和 CB2 大麻素受体的正向变构调节增强了双重 CB1R/CB2R 正构激动剂的神经保护活性

期刊:Life-Basel

影响因子:

doi:10.3390/life10120333

Beatrice Polini, Chiara Cervetto, Sara Carpi, Simone Pelassa, Francesca Gado, Rebecca Ferrisi, Simone Bertini, Paola Nieri, Manuela Marcoli, Clementina Manera

神经

发表日期：2020

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Watermelon: setup and validation of an in silico fragment-based approach

西瓜：基于碎片的计算机方法的设置和验证

A Proteomic Approach Identified TFEB as a Key Player in the Protective Action of Novel CB2R Bitopic Ligand FD22a against the Deleterious Effects Induced by β-Amyloid in Glial Cells

蛋白质组学方法确定 TFEB 是新型 CB2R 双位配体 FD22a 对抗 β-淀粉样蛋白在神经胶质细胞中引起的有害影响的保护作用中的关键因素

New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2

对 2 型大麻素受体双位正构/变构配体的新见解

Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands

新型 CB2 受体配体的设计、合成和生物活性：从正构和变构调节剂到双立体/双位配体

Achillea moschata Wulfen: From Ethnobotany to Phytochemistry, Morphology, and Biological Activity

蓍草：从民族植物学到植物化学、形态学和生物活性

Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells

选择性大麻素 CB2 受体激动剂的合成及体外表征：针对神经母细胞瘤癌细胞的生物学评价

Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R)

大麻素受体 2 型（CB2R）新型正构-变构配体的设计、合成及生物学评价

Liquid Chromatography-High-Resolution Mass Spectrometry (LC-HRMS) Profiling of Commercial Enocianina and Evaluation of Their Antioxidant and Anti-Inflammatory Activity

液相色谱-高分辨率质谱 (LC-HRMS) 对商用 Enocianina 进行分析并评估其抗氧化和抗炎活性

Anti-Inflammatory Activity of a CB2 Selective Cannabinoid Receptor Agonist: Signaling and Cytokines Release in Blood Mononuclear Cells

CB2 选择性大麻素受体激动剂的抗炎活性：血液单核细胞中的信号传导和细胞因子释放

Positive Allosteric Modulation of CB1 and CB2 Cannabinoid Receptors Enhances the Neuroprotective Activity of a Dual CB1R/CB2R Orthosteric Agonist

CB1 和 CB2 大麻素受体的正向变构调节增强了双重 CB1R/CB2R 正构激动剂的神经保护活性