日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

KIR2DS2+ NK cells in cancer patients demonstrate high activation in response to tumour-targeting antibodies

癌症患者体内的 KIR2DS2+ NK 细胞在响应肿瘤靶向抗体时表现出高度活化

Lara V Graham, Jack G Fisher, Amber D P Doyle, Ben Sale, Luis Del Rio, Albert J E French, Neema P Mayor, Thomas R Turner, Steven G E Marsh, Mark S Cragg, Francesco Forconi, Salim I Khakoo, Matthew D Blunt

XPO1 inhibition sensitises CLL cells to NK cell mediated cytotoxicity and overcomes HLA-E expression

XPO1 抑制可使 CLL 细胞对 NK 细胞介导的细胞毒性敏感,并克服 HLA-E 表达

Jack G Fisher, Amber D P Doyle, Lara V Graham, Shreyanshi Sonar, Ben Sale, Isla Henderson, Luis Del Rio, Peter W M Johnson, Yosef Landesman, Mark S Cragg, Francesco Forconi, Christopher J Walker, Salim I Khakoo, Matthew D Blunt

BTK-independent regulation of calcium signalling downstream of the B-cell receptor in malignant B-cells

BTK 独立调节恶性 B 细胞中 B 细胞受体下游的钙信号

Rachael Arthur, Alexander Wathen, Elizabeth A Lemm, Freda K Stevenson, Francesco Forconi, Adam J Linley, Andrew J Steele, Graham Packham, Beatriz Valle-Argos

B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells

细胞受体信号通过恶性 B 细胞中的 MEK1/2 和 mTORC1 诱导蛋白酶体降解 PDCD4

Joe Taylor, Sarah Wilmore, Sophie Marriot, Karly-Rai Rogers-Broadway, Rachel Fell, Annabel R Minton, Tom Branch, Meg Ashton-Key, Mark Coldwell, Freda K Stevenson, Francesco Forconi, Andrew J Steele, Graham Packham, Alison Yeomans

B-cell receptor dependent phagocytosis and presentation of particulate antigen by chronic lymphocytic leukemia cells

慢性淋巴细胞白血病细胞的B细胞受体依赖性吞噬作用和颗粒抗原呈递

Annabel R Minton, Lindsay D Smith, Dean J Bryant, Jonathan C Strefford, Francesco Forconi, Freda K Stevenson, David A Tumbarello, Edd James, Geir Åge Løset, Ludvig A Munthe, Andrew J Steele #, Graham Packham #

Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells

Kinobead 分析揭示了原发性 CLL 细胞内 BCR 信号在治疗后发生重编程

Adam J Linley, Laura I Karydis, Anil K Mondru, Annalisa D'Avola, Humood Al Shmrany, Silvia Cicconi, Rebecca Griffin, Francesco Forconi, Andrew R Pettitt, Nagesh Kalakonda, Andrew C Rawstron, Peter Hillmen, Andrew J Steele, David J MacEwan, Graham Packham, Ian A Prior, Joseph R Slupsky

Targeted inhibition of eIF4A suppresses B-cell receptor-induced translation and expression of MYC and MCL1 in chronic lymphocytic leukemia cells

靶向抑制 eIF4A 可抑制慢性淋巴细胞白血病细胞中 B 细胞受体诱导的翻译以及 MYC 和 MCL1 的表达

Sarah Wilmore, Karly-Rai Rogers-Broadway, Joe Taylor, Elizabeth Lemm, Rachel Fell, Freda K Stevenson, Francesco Forconi, Andrew J Steele, Mark Coldwell, Graham Packham, Alison Yeomans

DC-SIGN binding to mannosylated B-cell receptors in follicular lymphoma down-modulates receptor signaling capacity

DC-SIGN 与滤泡性淋巴瘤中的甘露糖化 B 细胞受体结合,下调受体信号传导能力

Beatriz Valle-Argos, Giorgia Chiodin, Dean J Bryant, Joe Taylor, Elizabeth Lemm, Patrick J Duriez, Philip J Rock, Jonathan C Strefford, Francesco Forconi, Richard W Burack, Graham Packham, Freda K Stevenson

Selinexor Enhances NK Cell Activation Against Malignant B Cells via Downregulation of HLA-E

Selinexor 通过下调 HLA-E 增强 NK 细胞对恶性 B 细胞的活化

Jack G Fisher, Christopher J Walker, Amber Dp Doyle, Peter Wm Johnson, Francesco Forconi, Mark S Cragg, Yosef Landesman, Salim I Khakoo, Matthew D Blunt

Genome-wide promoter methylation of hairy cell leukemia

毛细胞白血病的全基因组启动子甲基化

Arribas, Alberto J; Rinaldi, Andrea; Chiodin, Giorgia; Kwee, Ivo; Mensah, Afua Adjeiwaa; Cascione, Luciano; Rossi, Davide; Kanduri, Meena; Rosenquist, Richard; Zucca, Emanuele; Johnson, Peter W; Gaidano, Gianluca; Oakes, Christopher C; Bertoni, Francesco; Forconi, Francesco