Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents
基于结构的新型异喹诺酮和吡唑并[4,3-c]吡啶类fascin 1抑制剂的设计、合成和生物学评价,作为潜在的抗转移药物
期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2019.01.035
Francis, Stuart; Croft, Daniel; Schüttelkopf, Alexander W; Parry, Charles; Pugliese, Angelo; Cameron, Ken; Claydon, Sophie; Drysdale, Martin; Gardner, Claire; Gohlke, Andrea; Goodwin, Gillian; Gray, Christopher H; Konczal, Jennifer; McDonald, Laura; Mezna, Mokdad; Pannifer, Andrew; Paul, Nikki R; Machesky, Laura; McKinnon, Heather; Bower, Justin