日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Phenotype onset in Huntington's disease knock-in mice is correlated with the incomplete splicing of the mutant huntingtin gene.

亨廷顿病基因敲入小鼠的表型出现与突变亨廷顿基因的不完全剪接有关

期刊:Journal of Neuroscience Research
影响因子:3.4
doi:10.1002/jnr.24493
Franich Nicholas R, Hickey Miriam A, Zhu Chunni, Osborne Georgina F, Ali Nadira, Chu Tiffany, Bove Nicholas H, Lemesre Vincent, Lerner Renata P, Zeitlin Scott O, Howland David, Neueder Andreas, Landles Christian, Bates Gillian P, Chesselet Marie-Francoise
发表日期：2019
文献求助 收藏

Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease

CAG 140 基因敲入小鼠神经病理学和转录缺陷的改善支持了膳食姜黄素对亨廷顿病的有益作用。

期刊:Molecular Neurodegeneration
影响因子:17.5
doi:10.1186/1750-1326-7-12
Hickey, Miriam A; Zhu, Chunni; Medvedeva, Vera; Lerner, Renata P; Patassini, Stefano; Franich, Nicholas R; Maiti, Panchanan; Frautschy, Sally A; Zeitlin, Scott; Levine, Michael S; Chesselet, Marie-Françoise
发表日期：2012
文献求助 收藏

Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease

在亨廷顿病缓慢进展小鼠模型中，早期补充辅酶Q10的膳食疗法显示出行为益处的证据

期刊:Molecular and Cellular Neuroscience
影响因子:2.4
doi:10.1016/j.mcn.2011.10.007
Hickey, Miriam A; Zhu, Chunni; Medvedeva, Vera; Franich, Nicholas R; Levine, Michael S; Chesselet, Marie-Françoise
发表日期：2012
文献求助 收藏

AAV vector-mediated RNAi of mutant huntingtin expression is neuroprotective in a novel genetic rat model of Huntington's disease

在亨廷顿病的新型遗传大鼠模型中，AAV载体介导的RNAi抑制突变亨廷顿蛋白的表达具有神经保护作用。

期刊:Molecular Therapy
影响因子:12
doi:10.1038/mt.2008.50
Franich, Nicholas R; Fitzsimons, Helen L; Fong, Dahna M; Klugmann, Matthias; During, Matthew J; Young, Deborah
Rat
发表日期：2008
文献求助 收藏