日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Role for Two Conserved Arginine Residues in Protected Persulfide Transfer by SufE-Dependent SufS Cysteine Desulfurases

SufE依赖性SufS半胱氨酸脱硫酶在保护性过硫化物转移中发挥两个保守精氨酸残基的作用

Gogar, Rajleen K; Conte, Juliana V; Chhikara, Nidhi; Dunkle, Jack A; Frantom, Patrick A

Characterization of a mechanistic connection between persulfide transfer and ATP hydrolysis in the SufBC2D scaffold of the Suf Fe-S cluster assembly pathway

对 Suf Fe-S 簇组装途径中 SufBC2D 支架中过硫化物转移与 ATP 水解之间的机制联系进行表征

Chhikara, Nidhi; Timilsina, Grishma; Wang, Yu; Reasons, Dexter; Outten, F Wayne; Frantom, Patrick A

The structure of the SufS-SufE complex reveals interactions driving protected persulfide transfer in iron-sulfur cluster biogenesis

SufS-SufE复合物的结构揭示了驱动铁硫簇生物合成过程中受保护的过硫化物转移的相互作用。

Gogar, Rajleen K; Chhikara, Nidhi; Vo, Minh; Gilbert, Nathaniel C; Dunkle, Jack A; Frantom, Patrick A

Structural and functional characterization of fosfomycin resistance conferred by FosB from Enterococcus faecium

粪肠球菌 FosB 赋予的磷霉素耐药性的结构和功能表征

Wiltsie, Vanessa; Travis, Skye; Shay, Madeline R; Simmons, Zachary; Frantom, Patrick; Thompson, Matthew K

Structural evidence for a latch mechanism regulating access to the active site of SufS-family cysteine desulfurases

结构证据表明,存在一种闩锁机制调控SufS家族半胱氨酸脱硫酶活性位点的进入。

Dunkle, Jack A; Bruno, Michael R; Frantom, Patrick A

Characterization of the genomically encoded fosfomycin resistance enzyme from Mycobacterium abscessus

对脓肿分枝杆菌基因组编码的磷霉素抗性酶进行表征

Travis, Skye; Shay, Madeline R; Manabe, Shino; Gilbert, Nathaniel C; Frantom, Patrick A; Thompson, Matthew K

Changes in Protein Dynamics in Escherichia coli SufS Reveal a Possible Conserved Regulatory Mechanism in Type II Cysteine Desulfurase Systems

大肠杆菌 SufS 中蛋白质动力学的变化揭示了 II 型半胱氨酸脱硫酶系统中可能存在的保守调控机制

Dokyong Kim, Harsimran Singh, Yuyuan Dai, Guangchao Dong, Laura S Busenlehner, F Wayne Outten, Patrick A Frantom

UDP-(5F)-GlcNAc acts as a slow-binding inhibitor of MshA, a retaining glycosyltransferase

UDP-(5F)-GlcNAc 是一种 MshA(一种保留型糖基转移酶)的慢结合抑制剂。

Frantom, Patrick A; Coward, James K; Blanchard, John S

Chemoenzymatic synthesis of GDP-L-fucose and the Lewis X glycan derivatives

GDP-L-岩藻糖和Lewis X聚糖衍生物的化学酶法合成

Wang, Wei; Hu, Tianshun; Frantom, Patrick A; Zheng, Tianqing; Gerwe, Brian; Del Amo, David Soriano; Garret, Sarah; Seidel, Ronald D 3rd; Wu, Peng

Direct spectroscopic evidence for a high-spin Fe(IV) intermediate in tyrosine hydroxylase

酪氨酸羟化酶中高自旋Fe(IV)中间体的直接光谱证据

Eser, Bekir E; Barr, Eric W; Frantom, Patrick A; Saleh, Lana; Bollinger, J Martin Jr; Krebs, Carsten; Fitzpatrick, Paul F