日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combined computational and classical medicinal chemistry procedure to disclose novel pyrrole-based compounds as potential antituberculosis agents

结合计算和经典药物化学方法,发现新型吡咯类化合物作为潜在的抗结核药物。

Ragno, Rino; Zwergel, Clemens; Valente, Sergio; Astolfi, Roberta; Lambona, Chiara; Proia, Eleonora; Giuliani, Lidia; Franzblau, Scott G; Fioravanti, Rossella; Mai, Antonello

Selectivity of the Time-Dependent M. tuberculosis LeuRS Inhibitor Ganfeborole Is Driven by Target Vulnerability

时间依赖性结核分枝杆菌亮氨酸合成酶抑制剂甘非硼罗的选择性受靶标脆弱性驱动

Wang, Mingqian; He, YongLe; Cohen, Siobhan A; Strohm, Amanda R; Shetye, Gauri; Franzblau, Scott G; Walker, Stephen G; Alley, M R K; Tonge, Peter J

Expanding the Landscape of Dual Action Antifolate Antibacterials through 2,4-Diamino-1,6-dihydro-1,3,5-triazines

通过 2,4-二氨基-1,6-二氢-1,3,5-三嗪类化合物拓展双效抗叶酸抗菌药物的领域

Georgiades, John D; Berkovich, Daniel A; McKee, Samuel R; Smith, Angela R; Sankaran, Banumathi; Flentie, Kelly N; Castañeda, Carlos H; Grohmann, Daniel G; Rohatgi, Ram; Lasky, Carrie; Mason, Twila A; Champine, James E; Miller, Patricia A; Möllmann, Ute; Moraski, Garrett C; Franzblau, Scott G; Miller, Marvin J; Stallings, Christina L; Jez, Joseph M; Hathaway, Bruce A; Wencewicz, Timothy A

Structure-Based Analysis of Semisynthetic Anti-TB Rufomycin Analogues

半合成抗结核药物鲁福霉素类似物的基于结构的分析

Zhou, Bin; Shetye, Gauri; Klein, Larry L; Wolf, Nina M; Lee, Hyun; McAlpine, James B; Harris, Guy; Chen, Shao-Nong; Suh, Joo Won; Cho, Sang-Hyun; Franzblau, Scott G; Abad-Zapatero, Celerino; Pauli, Guido F

Isolation and Characterization of Anti-Mycobacterial Natural Products from a Petrosia sp. Marine Sponge

从一种Petrosia sp.海洋海绵中分离和鉴定抗分枝杆菌天然产物

Khatri Chhetri, Bhuwan; Bhanushali, Riya; Liang, Yifan; Cepeda, Marisa R; Niradininoco, Adi Kula; Soapi, Katy; Wan, Baojie; Qader, Mallique; Franzblau, Scott G; Kubanek, Julia

Microbiological Screening of 5-Functionalized Pyrazoles for the Future Development of Optimized Pyrazole-Based Delivery Systems

对5-功能化吡唑进行微生物筛选,以期未来开发优化的吡唑基递送系统

Brullo, Chiara; Caviglia, Debora; Spallarossa, Andrea; Alfei, Silvana; Franzblau, Scott G; Tasso, Bruno; Schito, Anna Maria

New Rufomycins from Streptomyces atratus MJM3502 Expand Anti-Mycobacterium tuberculosis Structure-Activity Relationships

来自链霉菌MJM3502的新型鲁福霉素拓展了抗结核分枝杆菌的构效关系

Zhou, Bin; Shetye, Gauri; Wolf, Nina M; Chen, Shao-Nong; Qader, Mallique; Ray, G Joseph; Lankin, David C; Cho, Sanghyun; Cheng, Jinhua; Suh, Joo-Won; Franzblau, Scott G; McAlpine, James B; Pauli, Guido F

Syntheses and studies of deuterated Imdiazo[1,2-a]pyridine-3-carboxamides with potent anti-tuberculosis activity and improved metabolic properties

合成及研究具有强效抗结核活性和改善的代谢特性的氘代咪唑并[1,2-a]吡啶-3-甲酰胺类化合物

Liu, Rui; Marshall, Kate; Ma, Rui; Lien Thi Pham, Kim; Shetye, Gauri; Liu, Zhihao; Cho, Sanghyun; Jeong, Hyunyoung; Franzblau, Scott G; Moraski, Garrett C; Miller, Marvin J

Insights into the Chemical Diversity of Selected Fungi from the Tza Itzá Cenote of the Yucatan Peninsula

尤卡坦半岛 Tza Itzá Cenote 中部分真菌化学多样性的研究进展

Fajardo-Hernández, Carlos A; Khan, Firoz Shah Tuglak; Flores-Bocanegra, Laura; Prieto-Davó, Alejandra; Wan, Baojie; Ma, Rui; Qader, Mallique; Villanueva-Silva, Rodrigo; Martínez-Cárdenas, Anahí; López-Lobato, Marian A; Hematian, Shabnam; Franzblau, Scott G; Raja, Huzefa A; García-Contreras, Rodolfo; Figueroa, Mario

Anti-Microbial Activity of Aliphatic Alcohols from Chinese Black Cardamom (Amomum tsao-ko) against Mycobacterium tuberculosis H37Rv

中国黑豆蔻(Amomum tsao-ko)中脂肪醇对结核分枝杆菌H37Rv的抗菌活性

Lee, So Young; Shetye, Gauri S; Son, So-Ri; Lee, Hyun; Klein, Larry L; Yoshihara, Jeffrey K; Ma, Rui; Franzblau, Scott G; Cho, Sanghyun; Jang, Dae Sik