日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis of TMPRSS11D specificity and autocleavage activation.

TMPRSS11D 特异性和自切割激活的结构基础

Fraser Bryan J, Wilson Ryan P, Ferková Sára, Ilyassov Olzhas, Lac Jackie, Dong Aiping, Li Yen-Yen, Seitova Alma, Li Yanjun, Hejazi Zahra, Kenney Tristan M G, Penn Linda Z, Edwards Aled, Leduc Richard, Boudreault Pierre-Luc, Morin Gregg B, Bénard François, Arrowsmith Cheryl H

Large Library Docking and Biophysical Analysis of Small-Molecule TMPRSS2 Inhibitors

大型化合物库对接及小分子TMPRSS2抑制剂的生物物理分析

Fraser, Bryan J; Young, Nicholas J; Bender, Brian J; Gahbauer, Stefan; Ilyassov, Olzhas; Wilson, Ryan P; Li, Yanjun; Seitova, Almagul; Lourenço, André Luiz; Chung, Dong Hee; Bardine, Conner; Bénard, François; Shoichet, Brian K; Craik, Charles S; Arrowsmith, Cheryl H

From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 Variants.

从 N-0385 到 N-0920:揭示了一种宿主导向的蛋白酶抑制剂,对流行的 SARS-CoV-2 变种具有皮摩尔级的抗病毒功效

Lemieux Gabriel, Pérez-Vargas Jimena, Désilets Antoine, Hassanzadeh Malihe, Thompson Connor A H, Gravel-Trudeau Alice, Joushomme Alexandre, Ennis Siobhan, Villanueva Ivan, Marouseau Étienne, Fraser Bryan J, Champagne William, Lepage Matthieu, Niikura Masahiro, Arrowsmith Cheryl H, Jean François, Leduc Richard, Boudreault Pierre-Luc