Fraser Iain D相关文献与解析，生知库 | 链接生命科学的每一步

SIGNAL: A web-based iterative analysis platform integrating pathway and network approaches optimizes hit selection from genome-scale assays

SIGNAL：一个基于网络的迭代分析平台，整合了通路和网络方法，可优化基因组规模检测中的命中筛选。

期刊:

影响因子:

doi:10.1016/j.cels.2021.03.001

Katz, Samuel; Song, Jian; Webb, Kyle P; Lounsbury, Nicolas W; Bryant, Clare E; Fraser, Iain D C

信号转导

发表日期：2021

文献求助收藏

Single-tube genotyping for small insertion/deletion mutations: simultaneous identification of wild type, mutant and heterozygous alleles

单管基因分型法检测小片段插入/缺失突变：同时鉴定野生型、突变型和杂合型等位基因

期刊:Biology Methods and Protocols

影响因子:1.3

doi:10.1093/biomethods/bpaa007

Lin, Bin; Sun, Jing; Fraser, Iain D C

发表日期：2020

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Distinct NF-κB and MAPK Activation Thresholds Uncouple Steady-State Microbe Sensing from Anti-pathogen Inflammatory Responses

不同的 NF-κB 和 MAPK 激活阈值使稳态微生物感知与抗病原体炎症反应脱钩

期刊:Cell Systems

影响因子:7.7

doi:10.1016/j.cels.2016.04.016

Gottschalk, Rachel A; Martins, Andrew J; Angermann, Bastian R; Dutta, Bhaskar; Ng, Caleb E; Uderhardt, Stefan; Tsang, John S; Fraser, Iain D C; Meier-Schellersheim, Martin; Germain, Ronald N

Switching of the relative dominance between feedback mechanisms in lipopolysaccharide-induced NF-ÎºB signaling.

脂多糖诱导的 NF-κB 信号传导中反馈机制相对优势的转变

期刊:Science Signaling

影响因子:6.6

doi:10.1126/scisignal.2004764

Sung Myong-Hee, Li Ning, Lao Qizong, Gottschalk Rachel A, Hager Gordon L, Fraser Iain D C

Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q

Gαi 和 Gαq 偶联的 G 蛋白偶联受体的协同 Ca2+ 反应需要一种对 Gβγ 和 Gαq 都敏感的单一 PLCβ 亚型。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M110.198200

Rebres, Robert A; Roach, Tamara I A; Fraser, Iain D C; Philip, Finly; Moon, Christina; Lin, Keng-Mean; Liu, Jamie; Santat, Leah; Cheadle, Lucas; Ross, Elliott M; Simon, Melvin I; Seaman, William E

信号转导

发表日期：2011

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Variability in G-protein-coupled signaling studied with microfluidic devices

利用微流控装置研究G蛋白偶联信号传导的变异性

期刊:Biophysical Journal

影响因子:3.1

doi:10.1016/j.bpj.2010.08.043

Bao, Xiaoyan Robert; Fraser, Iain D C; Wall, Estelle A; Quake, Stephen R; Simon, Melvin I

信号转导

发表日期：2010

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Navigating the network: signaling cross-talk in hematopoietic cells

网络导航：造血细胞中的信号串扰

期刊:Nature Immunology

影响因子:27.6

doi:10.1038/ni.1711

Fraser, Iain D C; Germain, Ronald N

Nigericin-Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

尼日利亚菌素触发的炎症小体形成和细胞焦亡中的磷酸化动力学

Efficient electroporation in primary cells with PEDOT:PSS electrodes

利用PEDOT:PSS电极在原代细胞中实现高效电穿孔

Lipid regulation of NLRP3 inflammasome activity through organelle stress

脂质通过细胞器应激调节NLRP3炎症小体活性

SIGNAL: A web-based iterative analysis platform integrating pathway and network approaches optimizes hit selection from genome-scale assays

SIGNAL：一个基于网络的迭代分析平台，整合了通路和网络方法，可优化基因组规模检测中的命中筛选。

Single-tube genotyping for small insertion/deletion mutations: simultaneous identification of wild type, mutant and heterozygous alleles

单管基因分型法检测小片段插入/缺失突变：同时鉴定野生型、突变型和杂合型等位基因

Distinct NF-κB and MAPK Activation Thresholds Uncouple Steady-State Microbe Sensing from Anti-pathogen Inflammatory Responses

不同的 NF-κB 和 MAPK 激活阈值使稳态微生物感知与抗病原体炎症反应脱钩

Switching of the relative dominance between feedback mechanisms in lipopolysaccharide-induced NF-ÎºB signaling.

脂多糖诱导的 NF-κB 信号传导中反馈机制相对优势的转变

Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q

Gαi 和 Gαq 偶联的 G 蛋白偶联受体的协同 Ca2+ 反应需要一种对 Gβγ 和 Gαq 都敏感的单一 PLCβ 亚型。

Variability in G-protein-coupled signaling studied with microfluidic devices

利用微流控装置研究G蛋白偶联信号传导的变异性

Navigating the network: signaling cross-talk in hematopoietic cells

网络导航：造血细胞中的信号串扰