日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cysteamine Inhibits Glycine Utilisation and Disrupts Virulence in Pseudomonas aeruginosa

半胱胺抑制甘氨酸利用并破坏铜绿假单胞菌的毒力

Douglas J Fraser-Pitt, Stephen K Dolan, David Toledo-Aparicio, Jessica G Hunt, Daniel W Smith, Niamh Lacy-Roberts, Piumi Sara Nupe Hewage, Teodora N Stoyanova, Erin Manson, Kevin McClean, Neil F Inglis, Derry K Mercer, Deborah A O'Neil

Cysteamine, an Endogenous Aminothiol, and Cystamine, the Disulfide Product of Oxidation, Increase Pseudomonas aeruginosa Sensitivity to Reactive Oxygen and Nitrogen Species and Potentiate Therapeutic Antibiotics against Bacterial Infection

半胱胺是一种内源性氨基硫醇,胱胺是氧化的二硫化物产物,可增加铜绿假单胞菌对活性氧和氮物质的敏感性,并增强治疗性抗生素对抗细菌感染的能力

Douglas J Fraser-Pitt, Derry K Mercer, Daniel Smith, Aleksandra Kowalczuk, Jennifer Robertson, Emma Lovie, Peter Perenyi, Michelle Cole, Michel Doumith, Robert L R Hill, Katie L Hopkins, Neil Woodford, Deborah A O'Neil

Activity of Cysteamine against the Cystic Fibrosis Pathogen Burkholderia cepacia Complex

半胱胺对囊性纤维化病原体洋葱伯克霍尔德菌复合体的活性

Fraser-Pitt, Douglas; Mercer, Derry; Lovie, Emma; Robertson, Jennifer; O'Neil, Deborah

Cysteamine as a Future Intervention in Cystic Fibrosis Against Current and Emerging Pathogens: A Patient-based ex vivo Study Confirming its Antimicrobial and Mucoactive Potential in Sputum

半胱胺作为囊性纤维化未来对抗现有和新出现的病原体的干预手段:一项基于患者的体外研究证实了其在痰液中的抗菌和粘液活性

Devereux, Graham; Fraser-Pitt, Douglas; Robertson, Jennifer; Devlin, Edward; Mercer, Derry; O'Neil, Deborah

Cystic fibrosis - a multiorgan protein misfolding disease

囊性纤维化——一种多器官蛋白质错误折叠疾病

Fraser-Pitt, Douglas; O'Neil, Deborah

Cysteamine (Lynovex®), a novel mucoactive antimicrobial & antibiofilm agent for the treatment of cystic fibrosis

半胱胺(Lynovex®),一种新型粘液活性抗菌和抗生物膜药物,用于治疗囊性纤维化

Charrier, Cedric; Rodger, Catherine; Robertson, Jennifer; Kowalczuk, Aleksandra; Shand, Nicola; Fraser-Pitt, Douglas; Mercer, Derry; O'Neil, Deborah